| Type | Description |
|---|---|
| Definition | phosphodiesterase 10A |
| Date | Results | Publications |
|---|---|---|
| 2018-09-15 11:55:00 | cAMP signaling pathway-related proteins, Pde10a and Gnal, may play important roles in the pathogenesis and recovery of mild traumatic brain injury. | 29215295 |
| 2016-09-03 12:18:00 | Through a combination of pharmacological and genetic tools, study provides convergent evidence of D2 (rather than D1) pathway dominant effects of PDE10A inhibition in rodents | 26256420 |
| 2012-08-04 10:23:00 | analysis of orally active pyrazoloquinolines as potent PDE10 inhibitors for the management of schizophrenia in the rat model | 22142545 |
| 2012-04-14 10:30:00 | Dopamine loss inversely regulates PDE10A gene expression in the striatum and PDE10A post-transcription in the nucleus accumbens, therein differentially modulating PDE10A-dependent cyclic AMP catabolism. | 21515371 |
| 2011-12-10 12:05:00 | Data show that pyridinyl derivatives were less potent than their quinolinyl counterparts, but still exhibited significant PDE10A inhibition potency. | 21777010 |
| Type | IDs |
|---|---|
| Synonymous | Pde10a3 |
| Gene |
UniProtKB-ID:
PDE10_RAT
UniprotKB:
Q9QYJ6
UniParc:
UPI0000353CA4,
UPI0000353CA6,
UPI00000E636C,
UPI0000353CA7,
UPI0000353CA5,
UPI00000E6619
EMBL:
AY462094,
AB027156,
AY462095,
AY462091,
AY462092,
AY462093,
CH474059,
AB027155
Ensembl:
ENSRNOG00000011310
KO:
rno:63885
|
| Nucleutide sequences |
EMBL-CDS:
EDL83106.1,
AAS21245.1,
AAS21244.1,
BAA88997.1,
AAS21247.1,
AAS21246.1,
AAS21243.1,
BAA88996.1
Ensembl_TRS:
ENSRNOT00000043474
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000042134
RefSeq:
NP_071572.1,
NP_001375438.1,
NP_001375440.1,
NP_001375439.1
|
| Others |
UniRef100:
UniRef100_Q9QYJ6
UniRef90:
UniRef90_Q9Y233
UniRef50:
UniRef50_Q9Y233
UniGene:
Rn.44869
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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