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63826 SRR

63826

SRR

serine racemase

protein-coding

Homo sapiens

基因描述

Type Description
Definition serine racemase

研究结论

Date Results Publications
2021-04-17 13:17:00 Human serine racemase is inhibited by glyceraldehyde 3-phosphate, but not by glyceraldehyde 3-phosphate dehydrogenase. 32971286
2020-08-29 12:44:00 Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients. 31621607
2019-11-30 10:12:00 these findings suggest that d-serine expressed particularly strongly in atopic dermatitis lesional skin and that the Serine racemase (SR) expression in the keratinocytes is linked to inflammatory cytokines. 29566294
2019-10-26 11:57:00 Results indicate glutamine 89 (Q89) as a key residue for the allosteric communication, since its mutation is linked to the loss of control of activity by nucleotides. 29899358
2019-10-19 12:31:00 SRR intronic variation inhibits expression of its neighboring SMG6 gene and protects against temporal lobe epilepsy. 29363864

名称对应

Type IDs
Synonymous ILV1, ISO1
Gene
UniProtKB-ID: SRR_HUMAN, Q8N3F4_HUMAN, Q3ZK31_HUMAN
UniprotKB: Q9GZT4, Q8N3F4, Q3ZK31
UniParc: UPI00005AB2A1, UPI0000073FCF, UPI00000015D7
EMBL: AY743706, AK023169, AL450226, BC074728, AY743707, AY743705, AY743708, AY034081, AL834378, AF169974, CH471108, CR457300
Ensembl: ENSG00000167720
KO: hsa:63826
Nucleutide sequences
EMBL-CDS: EAW90554.1, AAG27081.1, EAW90553.1, AAK58495.1, CAG33581.1, BAB14442.1, AAH74728.1, EAW90555.1, CAD39041.1, AAW66460.1, AAW66461.1, AAW66463.1, AAW66462.1
Ensembl_TRS: ENST00000344595, ENST00000574229, ENST00000572709
Protein sequencees
Ensembl_PRO: ENSP00000339435, ENSP00000458814, ENSP00000461482
RefSeq: XP_006721628.1, XP_011522276.1, NP_068766.1, XP_006721629.1, NP_001291732.1
Others
UniRef100: UniRef100_I3L3N0, UniRef100_Q9GZT4
UniRef90: UniRef90_Q9GZT4
UniRef50: UniRef50_Q9GZT4
UniGene: Hs.461954
CCDS: CCDS11017.1

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