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6373 CXCL11

6373

CXCL11

C-X-C motif chemokine ligand 11

protein-coding

Homo sapiens

基因描述

Type Description
Definition C-X-C motif chemokine ligand 11

研究结论

Date Results Publications
2021-01-23 13:02:00 Endothelial cells under therapy-induced senescence secrete CXCL11, which increases aggressiveness of breast cancer cells. 32659248
2020-09-12 16:04:00 The combination of CXCL9, CXCL10 and CXCL11 levels during primary HIV infection predicts HIV disease progression. 31836011
2020-07-04 12:13:00 serum CXCL11 and CXCL12 levels were elevated in cirrhotic patients 30826602
2020-01-25 14:47:00 Study confirmed that CXCL11 expression was significantly upregulated in hepatocellular carcinoma (HCC) alpha2delta1+ tumor-initiating cells (TICs) and that it played a crucial role in the acquirement and subsequent maintenance of self-renewal and tumorigenic abilities of HCC alpha2delta1+ TICs through the CXCR3/ERK1/2 signaling axis via autocrine signaling. 30771435
2019-08-10 12:27:00 These findings identify a feed-forward mechanism that sustains activation of the CXCR7/CXCL11 axis under ERalpha control to induce the epithelial-mesenchymal transition pathway and metastatic behavior of ovarian cancer cells. 30051594

名称对应

Type IDs
Synonymous H174, I-TAC, IP-9, IP9, SCYB11, SCYB9B, b-R1
Gene
UniProtKB-ID: CXL11_HUMAN
UniprotKB: O14625
UniParc: UPI0000030067
EMBL: BC005292, AF077867, Y15221, U66096, BT006787, AF002985, Y15220, AF030514, BC012532, AF053972, U59286, BC110986
Ensembl: ENSG00000169248
KO: hsa:6373
Nucleutide sequences
EMBL-CDS: AAC39775.1, CAB51859.1, AAD38867.1, AAD10206.1, CAA75510.1, AAC51845.1, AAD38327.1, AAH05292.1, AAB17374.1, AAH12532.1, AAI10987.1, AAP35433.1
Ensembl_TRS: ENST00000306621, ENST00000503860
Protein sequencees
Ensembl_PRO: ENSP00000425819, ENSP00000306884
RefSeq: NP_005400.1, NP_001289052.1
Others
UniRef100: UniRef100_O14625
UniRef90: UniRef90_O14625
UniRef50: UniRef50_O14625
UniGene: Hs.632592
CCDS: CCDS3574.1

全选

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