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637 BID

637

BID

BH3 interacting domain death agonist

protein-coding

Homo sapiens

基因描述

Type Description
Definition BH3 interacting domain death agonist

研究结论

Date Results Publications
2020-09-05 13:53:00 BID and the alpha-bisabolol-triggered cell death program: converging on mitochondria and lysosomes. 31767857
2020-07-25 10:08:00 The findings suggest that the cleaved Bid protein acts as an amplifier of apoptotic signaling through mitochondria, thus enhancing the activity of cysteine cathepsins following stefin B degradation. 30652348
2019-03-16 12:47:00 Differential roles for FL_BID and t-BID in Burkitt's lymphoma during apoptosis. There is a functional cooperation between BAK and BAX during VT-1-induced apoptosis and, unexpectedly, that activation of caspase-8 and production of t-BID were not mandatory for initiation of the cell death process. 29440708
2019-03-02 10:53:00 These results identify a role for Bid in homeostatic mitochondrial cristae reorganization, that we link to human cardiac disease. 30281024
2018-08-18 11:11:00 results suggest that histone modifications in the promoter region of miR-500a may be responsible for the increased expression of miR-500a in Hepatocellular carcinoma (HCC), which promotes cancer progression by targeting BID, indicating that miR-500a may be a potential prognostic predictor and therapeutic target for HCC patients. 29969781

名称对应

Type IDs
Synonymous FP497
Gene
UniProtKB-ID: BID_HUMAN, A8ASI8_HUMAN, B2ZP79_HUMAN, B3KT21_HUMAN
UniprotKB: P55957, A8ASI8, B2ZP79, B3KT21
UniParc: UPI00001D69F2, UPI0000001637, UPI00001D69F1, UPI00001B5F92, UPI0000372B4D
EMBL: CR456389, AY309922, BC022072, D89803, AF042083, CH471193, EU678293, AF250233, CR407603, AK094795, BC033634, BC036364, AK313729, BC009197, AF087891, AY005151, EU678294
Ensembl: ENSG00000015475
KO: hsa:637
Nucleutide sequences
EMBL-CDS: AAF89091.1, AAH36364.2, AAO32633.1, AAP97190.1, AAP50259.1, AAC34365.1, CAG30275.1, AAH09197.1, AAH33634.1, AAH22072.2, CAG28531.1, BAG36471.1, BAF79673.1, EAW57773.1, ACD47108.1, EAW57774.1, EAW57771.1, ACD47107.1, BAG52933.1
Gene_ORFName: hCG_21529, hCG_21529
Ensembl_TRS: ENST00000615414, ENST00000622694, ENST00000399765, ENST00000551952, ENST00000317361, ENST00000342111, ENST00000399774, ENST00000614949, ENST00000611040, ENST00000399767
Protein sequencees
Ensembl_PRO: ENSP00000318822, ENSP00000477773, ENSP00000344594, ENSP00000382669, ENSP00000483709, ENSP00000449236, ENSP00000480414, ENSP00000382674, ENSP00000483534, ENSP00000382667
RefSeq: NP_932071.1, NP_001231498.1, NP_001231496.1, NP_001187.1, NP_001231499.1, NP_932070.1, NP_001231501.1
Others
UniRef100: UniRef100_P55957, UniRef100_B3KT21
UniRef90: UniRef90_P55957
UniRef50: UniRef50_P55957
UniGene: Hs.591054
CCDS: CCDS13749.1, CCDS13747.1, CCDS13748.1

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