| Type | Description |
|---|---|
| Definition | tripartite motif-containing 71 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:40:00 | mRBPome capture identifies the RNA-binding protein TRIM71, an essential regulator of spermatogonial differentiation. | 32188631 |
| 2019-04-06 10:50:00 | A TRIM71 binding long noncoding RNA Trincr1 represses FGF/ERK signaling in embryonic stem cells. | 30911006 |
| 2018-03-31 11:39:00 | LIN41 interacts with p53, controls its abundance by ubiquitination and antagonizes p53-dependent pro-apoptotic and pro-differentiation responses. In vivo, lack of LIN41 is associated with upregulation of Grhl3 and widespread caspase-3 activation, 2 downstream effectors of p53 with essential roles in neural tube closure. | 28430184 |
| 2016-04-16 10:11:00 | suggest that Trim71 keeps priming steps of differentiation in check, which do not pre-require a loss of the pluripotency network in ES cells | 26057209 |
| 2013-11-30 10:47:00 | Two well-known E3 ubiquitin ligases, Trim25 (also called Efp) and Trim71 (also called Lin41), are validated as RNA-binding proteins, revealing a potential link between RNA biology and protein-modification pathways. | 23912277 |
| Type | IDs |
|---|---|
| Synonymous | 2610206G21Rik, AL022943, Gm1127, Lin41, lin-41, mLin41, mlin-41 |
| Gene |
UniProtKB-ID:
LIN41_MOUSE
UniprotKB:
Q1PSW8
UniParc:
UPI0000D5C12F
EMBL:
DQ005956
Ensembl:
ENSMUSG00000079259
KO:
mmu:636931
|
| Nucleutide sequences |
EMBL-CDS:
AAY55947.1
Ensembl_TRS:
ENSMUST00000111816
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000107447
RefSeq:
NP_001035968.1
|
| Others |
UniRef100:
UniRef100_Q1PSW8
UniRef90:
UniRef90_Q1PSW8
UniRef50:
UniRef50_Q1PSW8
UniGene:
Mm.17857
CCDS:
CCDS40793.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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