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6342 SCP2

6342

SCP2

sterol carrier protein 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition sterol carrier protein 2

研究结论

Date Results Publications
2020-01-11 11:39:00 Methylation dependent microRNA 1285-5p and sterol carrier proteins 2 in type 2 diabetes mellitus 31407919
2017-07-22 12:21:00 We (1) analyzed the structural basis of the fold and the classification of SCP2 domains; (2) identified structure-determined sequence features; (3) compared the lipid binding cavity of SCP2 and other lipid binding proteins; (4) surveyed proposed mechanisms of SCP2 mediated lipid transfer between membranes; and (5) uncovered a possible new function of the SCP2 domain as a protein-protein recognition device. 28284963
2017-05-06 10:44:00 imported protein sterol carrier protein 2 (SCP2) occupies only a subregion of larger peroxisomes, highlighting the heterogeneous distribution of proteins even within the peroxisome. 27311714
2017-03-11 12:48:00 Mice harboring a deletion of the Scp2 locus present a modulated diurnal accumulation of lipids in the liver and a perturbed activation of several signaling pathways including PPARalpha, SREBP, LRH-1, TORC1 and its upstream regulators. 27097688
2015-06-20 10:32:00 We conclude that SCP-2 is a low affinity binding protein for arachidonylethanolamine that can facilitate its cellular uptake but does not contribute significantly to intracellular sequestration of AEA. 24510313

名称对应

Type IDs
Synonymous NLTP, NSL-TP, SCP-2, SCP-CHI, SCP-X, SCPX
Gene
UniProtKB-ID: NLTP_HUMAN, B2R761_HUMAN, A0A384NY87_HUMAN, E9PLD1_HUMAN, Q59HG9_HUMAN
UniprotKB: P22307, B2R761, A0A384NY87, E9PLD1, Q59HG9
UniParc: UPI0001750615, UPI00004F6A52, UPI0001DD3808, UPI00004703B0, UPI0000D61F1F, UPI000034E592, UPI0000000C71, UPI000189169A, UPI00017A730D, UPI0000130258, UPI00004703AF
EMBL: U11305, U11299, AK308105, AK295214, BC067108, M75883, GQ891355, U11307, U11313, CR995014, M55421, CH471059, AL445183, U11306, U11303, U11297, AK294631, AC099677, U11308, U11310, U11304, U11311, AB208789, U11309, S52450, U11302, M75884, AK312856, U11301, BC005911, CB997588, U11300, U11312
Ensembl: ENSG00000116171
KO: hsa:6342
Nucleutide sequences
EMBL-CDS: AAH05911.1, AAB41286.1, AAA03557.1, BAG58208.1, EAX06761.1, AAA03559.1, BAG57810.1, AAH67108.1, AAB24921.1, EAX06760.1, AAA03558.1, BAG35708.1, ADO22217.1, BAD92026.1
Ensembl_TRS: ENST00000371514, ENST00000435345, ENST00000430330, ENST00000371513, ENST00000488965, ENST00000407246, ENST00000408941, ENST00000528311, ENST00000371509, ENST00000478631
Protein sequencees
Ensembl_PRO: ENSP00000435783, ENSP00000406636, ENSP00000434132, ENSP00000360568, ENSP00000396413, ENSP00000360569, ENSP00000360564, ENSP00000386214, ENSP00000384569, ENSP00000435194
RefSeq: NP_001007099.1, NP_001007100.1, XP_005271160.1, NP_002970.2, NP_001007251.1, NP_001007101.1, XP_011540237.1, NP_001180528.1, NP_001317516.1, NP_001180529.1, NP_001180546.1
Others
UniRef100: UniRef100_P22307, UniRef100_E9PLD1, UniRef100_B2R761
UniRef90: UniRef90_E9PLD1, UniRef90_P22307, UniRef90_G3R735
UniRef50: UniRef50_E9PLD1, UniRef50_P22307
UniGene: Hs.476365
CCDS: CCDS41338.1, CCDS53317.1, CCDS44149.1, CCDS572.1, CCDS53319.1, CCDS30719.1, CCDS53318.1, CCDS44150.1

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