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6341 SCO1

6341

SCO1

SCO cytochrome c oxidase assembly protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition SCO cytochrome c oxidase assembly protein 1

研究结论

Date Results Publications
2016-07-16 10:47:00 Results find that COA6 associates with COX2 and is crucial for its maturation and complex IV biogenesis. Also, COA6 interacts with the copper chaperone SCO1 which indicates that COA6 is intrinsically involved in the copper delivery process for COX2. 26160915
2015-12-26 11:49:00 Sco1 is a metallochaperone that selectively transfers Cu(I) ions based on loop recognition, whereas Sco2 is a copper-dependent thiol reductase of the cysteine ligands in the oxidase. 26351686
2015-01-17 12:42:00 COX20 cooperates with SCO1 and SCO2 to mature COX2 and promote the assembly of cytochrome c oxidase. 24403053
2013-09-14 10:36:00 COX19 is necessary for the transduction of a SCO1-dependent mitochondrial redox signal that regulates ATP7A-mediated cellular copper efflux. 23345593
2011-03-26 11:26:00 Results describe the tissue distribution of SCO1 and SCO2 in mouse and human tissues. 20864674

名称对应

Type IDs
Synonymous SCOD1
Gene
UniProtKB-ID: SCO1_HUMAN
UniprotKB: O75880
UniParc: UPI000013566A
EMBL: AF295384, AF295383, AF131816, AK315595, AF295386, AF183424, AF026852, AF295381, AF295382, BC015504, AF295385, CH471108
Ensembl: ENSG00000133028
KO: hsa:6341
Nucleutide sequences
EMBL-CDS: EAW89997.1, AAG23836.1, AAD08641.1, AAD20051.1, AAG09693.1, BAG37967.1, AAH15504.1
Ensembl_TRS: ENST00000255390
Protein sequencees
Ensembl_PRO: ENSP00000255390
RefSeq: NP_004580.1
Others
UniRef100: UniRef100_O75880
UniRef90: UniRef90_O75880
UniRef50: UniRef50_O75880
UniGene: Hs.14511
CCDS: CCDS11158.1

全选

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