| Type | Description |
|---|---|
| Definition | sodium voltage-gated channel alpha subunit 10 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:32:00 | Pathogenic mutations perturb calmodulin regulation of Nav1.8 channel. | 32948286 |
| 2020-10-31 13:12:00 | Comparable clinical characteristics in Brugada syndrome patients harboring SCN5A or novel SCN10A variants. | 31292628 |
| 2020-09-26 13:04:00 | Impact of the NaV1.8 variant, A1073V, on post-sigmoidectomy pain and electrophysiological function in rat sympathetic neurons. | 31642403 |
| 2020-07-11 11:52:00 | Our results suggest that the rs11708996 and rs10428132 polymorphisms of the SCN5A and SCN10A genes may contribute to an elevated risk of developing VA [ventricular arrhythmia] in the context of MI[myocardial infarction]. The associated alleles or genotypes may be used to predict the risk, and thus prevent eventual SCD [sudden cardiac death. | 32330377 |
| 2020-06-06 12:29:00 | Functional NaV1.8 channels are absent in non-diseased atrial and ventricular cardiac myocytes. | 31916131 |
| Type | IDs |
|---|---|
| Synonymous | FEPS2, Nav1.8, PN3, SNS, hPN3 |
| Gene |
UniProtKB-ID:
SCNAA_HUMAN
UniprotKB:
Q9Y5Y9
UniParc:
UPI0000209BDA
EMBL:
AC116038,
AC137625,
AF117907
Ensembl:
ENSG00000185313
KO:
hsa:6336
|
| Nucleutide sequences |
EMBL-CDS:
AAD30863.1
Ensembl_TRS:
ENST00000449082,
ENST00000644826
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000390600,
ENSP00000494789
RefSeq:
XP_005265428.1,
NP_001280236.2,
XP_011532296.1,
XP_011532295.1,
NP_001280235.2,
NP_006505.4
|
| Others |
UniRef100:
UniRef100_Q9Y5Y9
UniRef90:
UniRef90_Q9Y5Y9
UniRef50:
UniRef50_Q9Y5Y9
UniGene:
Hs.250443
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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