| Type | Description |
|---|---|
| Definition | sodium voltage-gated channel alpha subunit 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:26:00 | Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy. | 32185219 |
| 2020-12-05 13:03:00 | Differential Inhibition of Human Nav1.2 Resurgent and Persistent Sodium Currents by Cannabidiol and GS967. | 32244818 |
| 2020-10-24 14:12:00 | Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy. | 32845893 |
| 2020-06-27 11:24:00 | Genotype or allelic frequencies of SCN2A c.56 G > A gene polymorphism did not significantly differ for AG or GG genotypes in the non-responders vs. responders | 31707316 |
| 2020-05-09 13:52:00 | different epileptogenic point mutations in hNav1.2 have distinct biophysical effects on the channel, but also illustrates that individual mutations can have complex consequences that are difficult to identify using conventional analyses | 31558572 |
| Type | IDs |
|---|---|
| Synonymous | BFIC3, BFIS3, BFNIS, EIEE11, HBA, HBSCI, HBSCII, NAC2, Na(v)1.2, Nav1.2, SCN2A1, SCN2A2 |
| Gene |
UniProtKB-ID:
SCN2A_HUMAN
UniprotKB:
Q99250
UniParc:
UPI000002A663,
UPI00001279C9
EMBL:
AF327238,
AF327246,
AC011303,
AF327236,
AF327240,
AF327232,
AF327239,
AF327233,
AF327245,
AF327234,
AF327235,
AC013438,
X65361,
M91804,
M94055,
AF327230,
AF327237,
AF327244,
AF327241,
AF327228,
AF327242,
AF327243,
M55662,
AF327231,
AF327226,
AF059683,
AF327227,
AF327229
Ensembl:
ENSG00000136531
KO:
hsa:6326
|
| Nucleutide sequences |
EMBL-CDS:
AAG53413.1,
AAA18895.1,
CAA46438.1,
AAG53412.1,
AAB65854.2,
AAC14574.1,
AAY14971.1
Ensembl_TRS:
ENST00000637266,
ENST00000636071,
ENST00000631182,
ENST00000283256,
ENST00000375437,
ENST00000375427
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000283256,
ENSP00000364576,
ENSP00000490107,
ENSP00000490866,
ENSP00000486885,
ENSP00000364586
RefSeq:
NP_001035233.1,
NP_001358176.1,
XP_016860147.1,
NP_066287.2,
XP_016860145.1,
XP_024308805.1,
NP_001358175.1,
NP_001035232.1,
XP_016860148.1,
XP_016860146.1
|
| Others |
UniRef100:
UniRef100_Q99250
UniRef90:
UniRef90_Q99250
UniRef50:
UniRef50_Q99250
UniGene:
Hs.93485
CCDS:
CCDS33313.1,
CCDS33314.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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