| Type | Description |
|---|---|
| Definition | spermidine/spermine N1-acetyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:05:00 | Dengue virus targets RBM10 deregulating host cell splicing and innate immune response. | 32432721 |
| 2020-08-29 12:47:00 | Identification of TAF1, SAT1, and ARHGEF9 as DNA methylation biomarkers for hepatocellular carcinoma. | 31283007 |
| 2020-02-29 10:47:00 | CRISPR knockin mutants demonstrate the essentiality of the polyamine acetyltransferase activity of SAT1 for its function as a transcriptional regulator | 31399646 |
| 2019-09-07 11:06:00 | SSATX, an alternative splicing variant of the SAT1 gene, is proposed to function as a long non-coding RNA prior to its degradation in melanoma cells. | 31352009 |
| 2018-03-24 11:21:00 | Activation of SAT1 expression induces lipid peroxidation and sensitizes cells to undergo ferroptosis upon reactive oxygen species stress, which also leads to suppression of tumor growth in xenograft tumor models. Notably, SAT1 expression is down-regulated in human tumors, and CRISPR-cas9-mediated knockout of SAT1 expression partially abrogates p53-mediated ferroptosis. Moreover, SAT1 induction is correlated | 27698118 |
| Type | IDs |
|---|---|
| Synonymous | DC21, KFSD, KFSDX, SAT, SSAT, SSAT-1 |
| Gene |
UniProtKB-ID:
SAT1_HUMAN,
A0A384NQ10_HUMAN
UniprotKB:
P21673,
A0A384NQ10
UniParc:
UPI000012621E
EMBL:
CR450294,
GQ900981,
AK312162,
BC008424,
M77693,
BT006825,
U40369,
BC002503,
M55580,
CH471074,
Z14136
Ensembl:
ENSG00000130066
KO:
hsa:6303
|
| Nucleutide sequences |
EMBL-CDS:
AAA98854.1,
AAH02503.1,
AAP35471.1,
CAA78509.1,
BAG35096.1,
CAG29290.1,
AAA63260.1,
EAW99000.1,
AAH08424.1,
AAA60573.1,
ADO22498.1
Ensembl_TRS:
ENST00000379270
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000368572
RefSeq:
XP_024308189.1,
NP_002961.1
|
| Others |
UniRef100:
UniRef100_P21673
UniRef90:
UniRef90_P21673
UniRef50:
UniRef50_P21673
UniGene:
Hs.28491
CCDS:
CCDS14207.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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