| Type | Description |
|---|---|
| Definition | spalt like transcription factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-25 14:47:00 | In human glioblastoma cells and cerebral glioma tissues, SALL1 acted as a tumor suppressor gene by inhibiting Wnt/ss-catenin signaling. | 31040265 |
| 2019-08-03 10:32:00 | Data identified SALL1 as a novel tumor suppressor in breast cancer. SALL1 can induce tumor cell senescence as a novel mechanism of tumor suppressor function. This molecular process acts through NuRD recruitment and is controlled by the MAPK and mTOR signaling pathways. | 29625565 |
| 2018-12-22 11:57:00 | SALL1 mutations might cause Townes-Brocks Syndrome. | 29395072 |
| 2014-10-18 12:10:00 | Inhibition of SALL1 correlates with reduced levels of CDH1, an important contributor to epithelial-to-mesenchymal transition. | 24292671 |
| 2013-04-27 12:09:00 | quantity and quality of SALL1 transcript are important for SALL1 function and determine phenotype, and mode of inheritance, of allelic SALL1-related disorders | 23069192 |
| Type | IDs |
|---|---|
| Synonymous | HEL-S-89, HSAL1, Sal-1, TBS, ZNF794 |
| Gene |
UniProtKB-ID:
SALL1_HUMAN
UniprotKB:
Q9NSC2
UniParc:
UPI000013CCD8,
UPI0001756A94
EMBL:
Y18264,
Y18265,
AF074949,
X98833,
AK307835,
AC009166,
AF017655
Ensembl:
ENSG00000103449
KO:
hsa:6299
|
| Nucleutide sequences |
EMBL-CDS:
CAB41399.1,
CAB41400.1,
AAB99908.1,
AAF19263.1
Ensembl_TRS:
ENST00000440970,
ENST00000251020
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000251020,
ENSP00000407914
RefSeq:
NP_002959.2,
NP_001121364.1
|
| Others |
UniRef100:
UniRef100_Q9NSC2
UniRef90:
UniRef90_Q9NSC2
UniRef50:
UniRef50_Q9ER74
UniGene:
Hs.135787
CCDS:
CCDS10747.1,
CCDS45483.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员