| Type | Description |
|---|---|
| Definition | scaffold attachment factor B |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:51:00 | Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association. | 33257571 |
| 2020-04-04 11:35:00 | Depletion of SAFB leads to changes in 3D genome organization. | 31677973 |
| 2019-02-23 11:04:00 | SAFB1 binds to the HIV-1 LTR and physically interacts with phosphorylated RNA polymerase II, repressing HIV-1 transcription initiation and elongation. | 29887524 |
| 2018-06-23 11:08:00 | SAFB regulated the activity of NF-kappaB signaling in CRC by targeting TAK1 This novel mechanism provides a comprehensive understanding of both SAFB and the NF-kappaB signaling pathway in the progression of CRC and indicates that the SAFB-TAK1-NF-kappaB axis is a potential target for early therapeutic intervention in CRC progression | 28912140 |
| 2018-04-28 10:44:00 | Depletion of SAFB1 reduced FUS's localization to chromatin-bound fraction and splicing activity, suggesting SAFB1 could tether FUS to chromatin compartment thorough N-terminal DNA-binding motif. Moreover, FUS interacts with another nuclear matrix-associated protein, Matrin3. | 27731383 |
| Type | IDs |
|---|---|
| Synonymous | HAP, HET, SAB-B1, SAF-B, SAF-B1, SAFB1 |
| Gene |
UniProtKB-ID:
SAFB1_HUMAN,
B7ZLP5_HUMAN,
B7Z2F6_HUMAN
UniprotKB:
Q15424,
B7ZLP5,
B7Z2F6
UniParc:
UPI0000E5BE82,
UPI0000161FB7,
UPI0001F7E3C5,
UPI000189A72A,
UPI0001914C7B,
UPI0000203163
EMBL:
BC143939,
AK294671,
AK298707,
AC011499,
U72355,
AB208780,
BC143937,
BC143938,
AC004611,
AC134303,
L43631,
BC126219
Ensembl:
ENSG00000160633
KO:
hsa:6294
|
| Nucleutide sequences |
EMBL-CDS:
AAC14667.1,
AAI26220.1,
AAI43940.1,
AAI43938.1,
AAC00056.1,
BAD92017.1,
BAH12852.1,
AAC18697.1,
AAI43939.1,
BAH11842.1
Ensembl_TRS:
ENST00000454510,
ENST00000592224,
ENST00000588852,
ENST00000292123
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000415895,
ENSP00000464840,
ENSP00000467423,
ENSP00000292123
RefSeq:
NP_001307500.1,
NP_001188269.1,
NP_002958.2,
NP_001188268.1,
NP_001188267.1,
NP_001307501.1,
XP_016882603.1,
XP_016882605.1,
XP_016882604.1,
XP_016882607.1,
XP_016882606.1
|
| Others |
UniRef100:
UniRef100_Q15424,
UniRef100_B7ZLP5,
UniRef100_B7Z2F6
UniRef90:
UniRef90_Q15424,
UniRef90_B7Z2F6
UniRef50:
UniRef50_A0A452TZU9,
UniRef50_Q15424
UniGene:
Hs.728802
CCDS:
CCDS12142.1,
CCDS59340.1,
CCDS59339.1,
CCDS56077.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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