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6293 VPS52

6293

VPS52

VPS52 subunit of GARP complex

protein-coding

Homo sapiens

基因描述

Type Description
Definition VPS52 subunit of GARP complex

研究结论

Date Results Publications
2020-05-16 12:05:00 The Sac2 operates upstream of granule docking, since loss of Sac2 prevented granule tethering to the plasma membrane and resulted in both reduced granule density and number of exocytic events. 31533953
2018-06-23 10:36:00 Loss of heterozygosity and stop-gain mutation of VPS52 were found in gastric cancer. 28791438
2017-12-02 10:39:00 These data demonstrate that the beneficial properties of SFN extend beyond activation of the KEAP1-Nrf2-ARE system and warrant further interrogation given the current use of this agent in multiple clinical trials 27889639
2015-07-04 12:13:00 our data indicate that cisplatin resistance in HOCCs is partially attributable to their high expression of p62, which plays an important role in preventing stress-induced apoptosis by regulating the Keap1-Nrf2-ARE signaling pathway. 25269472
2010-10-27 14:29:00 Golgi-associated retrograde protein orchestrates retrograde transport from endosomes to the trans-Golgi network by promoting vesicle tethering and assembly of SNARE complexes in consecutive, independent steps.[Golgi associated retrograde protein] 19620288

名称对应

Type IDs
Synonymous ARE1, SAC2, SACM2L, dJ1033B10.5
Gene
UniProtKB-ID: VPS52_HUMAN, B4DS44_HUMAN, A0A1U9X8S4_HUMAN, B3KMF7_HUMAN, Q4VXZ2_HUMAN
UniprotKB: Q8N1B4, B4DS44, A0A1U9X8S4, B3KMF7, Q4VXZ2
UniParc: UPI00017A7C34, UPI000015F39A, UPI000006E468, UPI0000E20EDE
EMBL: CH471081, KY500731, CR759786, CR759817, BC040114, AL031228, AK297935, CR762434, KY500732, BC032108, BX248408, AK001725, AL645940, AK222867, AL390171, KY500730, AK299563
Ensembl: ENSG00000228425, ENSG00000223501, ENSG00000236014, ENSG00000206286, ENSG00000225590, ENSG00000224455
KO: hsa:6293
Nucleutide sequences
EMBL-CDS: BAG60251.1, AAH32108.1, BAD96587.1, CAI95619.1, CAB99099.1, EAX03688.1, AAH40114.2, BAG61506.1, AQY77200.1, AQY77201.1, AQY77202.1, BAG50969.1, CAI95618.1
Gene_ORFName: RP5-1033B10.17-001
Ensembl_TRS: ENST00000428608, ENST00000448042, ENST00000441058, ENST00000443860, ENST00000383210, ENST00000445902
Protein sequencees
Ensembl_PRO: ENSP00000409952, ENSP00000406988, ENSP00000391197, ENSP00000372697, ENSP00000404016, ENSP00000390831
RefSeq: XP_016866668.1, XP_024302287.1, NP_001276105.1, XP_011513101.1, NP_072047.4, NP_001276104.1, XP_011513100.1, XP_016866666.1, XP_011513099.1, XP_016866667.1, NP_001276103.1
Others
UniRef100: UniRef100_Q8N1B4, UniRef100_B3KMF7
UniRef90: UniRef90_A0A340XHF5, UniRef90_Q8N1B4
UniRef50: UniRef50_Q8N1B4
UniGene: Hs.480356
CCDS: CCDS4770.2

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