Type | Description |
---|---|
Definition | reticulon 1 |
Date | Results | Publications |
---|---|---|
2019-05-25 10:55:00 | Study findings show that RTN1A is a marker for cells of the dendritic lineage, including Langerhans cells and dermal dendritic cells. | 29369773 |
2019-02-02 10:59:00 | Results show that mice deficient in RTN1 are generally normal and that RTN1 is a predominantly expressed in the nervous system, mainly in neurons. In neurons, RTN1 is enriched in dendrites. Also, RTN1 deficiency shows no obvious effects on BACE1 activity due to compensation by RTN3, as RTN1 deficiency causes elevation of RTN3 expression suggesting that RTN1 does not have a prominent role in Alzheimer's pathogenesis. | 28733667 |
2017-10-21 12:52:00 | Data suggest that reticulon 1A (RTN1A) functions not only as an endoplasmic reticulum-shaping protein but also as a protein that promotes contacts between endoplasmic reticulum and mitochondria. | 28760823 |
2016-09-03 10:44:00 | Results suggest evidence of genetic association between common variants in RTN1 and end-stage kidney disease in African-Americans and European-Americans. | 26496126 |
2016-07-30 11:44:00 | RTN1A is a key mediator for proteinuria-induced tubular cell toxicity and renal fibrosis. | 26739891 |
Type | IDs |
---|---|
Synonymous | NSP |
Gene |
UniProtKB-ID:
RTN1_HUMAN,
A8K3B9_HUMAN
UniprotKB:
Q16799,
A8K3B9
UniParc:
UPI000002B2DE,
UPI00001352DA,
UPI000002B2DD,
UPI00015DA78E
EMBL:
AK290534,
BC000314,
L10335,
BC003003,
CH471061,
L10333,
L10334,
BC090862
Ensembl:
ENSG00000139970
KO:
hsa:6252
|
Nucleutide sequences |
EMBL-CDS:
AAA59950.1,
AAH03003.2,
AAH90862.1,
AAA59952.1,
AAH00314.2,
EAW80762.1,
AAA59951.1,
BAF83223.1
Ensembl_TRS:
ENST00000267484,
ENST00000342503
|
Protein sequencees |
Ensembl_PRO:
ENSP00000340716,
ENSP00000267484
RefSeq:
XP_011535365.1,
NP_066959.1,
NP_996734.1,
NP_001350631.1
|
Others |
UniRef100:
UniRef100_Q16799,
UniRef100_A8K3B9
UniRef90:
UniRef90_Q16799,
UniRef90_A8K3B9
UniRef50:
UniRef50_Q16799,
UniRef50_Q6IFY7
UniGene:
Hs.368626
CCDS:
CCDS9740.1,
CCDS9741.1
|
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