| Type | Description |
|---|---|
| Definition | ras responsive element binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:59:00 | Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes. | 32938917 |
| 2020-06-06 12:24:00 | Data show that RREB1-induced upregulation of AGAP2-AS1 regulates cell proliferation and migration in PC partly through suppressing ANKRD1 and ANGPTL4 by recruiting EZH2. | 30814490 |
| 2020-05-09 13:35:00 | identification of RAS-responsive element binding protein 1 (RREB1), a RAS transcriptional effector, as a key partner of TGF-beta-activated SMAD transcription factors in epithelial-to-mesenchymal transitions | 31915377 |
| 2020-02-22 10:46:00 | Findings demonstrated that RREB1 blocks granulocytic differentiation of myeloid leukemia cells by inhibiting the expression of miR-145 and downstream targets of the RAS signal pathway. | 30982491 |
| 2020-02-01 10:55:00 | Functional data indicate that modulating Ras-responsive element-binding protein 1 (RREB1) expression in human DLBCL cell lines in vitro alters KRAS expression, signaling, and proliferation; thus, suggesting that this proto-oncogene is a common mechanism of RAS/MAPK hyperactivation in human DLBCL. | 30355676 |
| Type | IDs |
|---|---|
| Synonymous | FINB, HNT, LZ321, RREB-1, Zep-1 |
| Gene |
UniProtKB-ID:
RREB1_HUMAN,
A0A024QZU8_HUMAN
UniprotKB:
Q92766,
A0A024QZU8
UniParc:
UPI0003D19F67,
UPI0001565469,
UPI000020E496,
UPI0003D19F63,
UPI0000480C9A,
UPI000020E495
EMBL:
BC042910,
AL589644,
U26914,
AB019351,
AF072826,
HM369360,
AL139095,
HM369361,
CH471087,
D49835,
AF072825,
AL355336,
AB019254,
AB019352,
BC131599
Ensembl:
ENSG00000124782
KO:
hsa:6239
|
| Nucleutide sequences |
EMBL-CDS:
BAD32779.1,
BAA23165.1,
AAH42910.1,
BAD32778.1,
AAB19094.1,
ADO14469.1,
AAI31600.1,
AAC25598.1,
AAC26118.1,
ADO14468.1,
BAD32776.1,
EAW55199.1,
EAW55200.1,
EAW55198.1
Gene_ORFName:
hCG_15864
Ensembl_TRS:
ENST00000379933,
ENST00000379938,
ENST00000334984,
ENST00000349384
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000305560,
ENSP00000369265,
ENSP00000369270,
ENSP00000335574
RefSeq:
NP_001161816.1,
NP_001003700.1,
NP_001003699.1,
NP_001003698.1
|
| Others |
UniRef100:
UniRef100_Q92766
UniRef90:
UniRef90_Q92766
UniRef50:
UniRef50_Q92766
UniGene:
Hs.298248
CCDS:
CCDS54963.1,
CCDS34335.1,
CCDS34336.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员