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6209 RPS15

6209

RPS15

ribosomal protein S15

protein-coding

Homo sapiens

基因描述

Type Description
Definition ribosomal protein S15

研究结论

Date Results Publications
2020-04-11 11:12:00 Findings suggest that the C-terminal tail of uS19 plays a key role in the accommodation of aa-tRNA at the A site. 31991215
2020-03-21 10:35:00 our findings demonstrate that the human ribosomal protein uS19 interacts with mRNAs during translation elongation and highlight the regions of mRNAs where ribosome pausing occurs, bringing new structural and functional insights into eukaryotic translation in vivo. 31802126
2019-08-03 12:43:00 Quantitative mass spectrometry analyses suggest that RPS15 variants may induce additional alterations in the translational machinery, as well as a metabolic shift at the proteome level in HEK293T and MEC-1 cells. These results indicate that chronic lymphocytic leukemia-related RPS15 mutations might act following patterns known for other ribosomal diseases. 30181176
2016-08-13 11:22:00 we provide novel insights into the heterogeneous genomic landscape of relapsing chronic lymphocytic leukemia and report recurrent mutations in a "hotspot" region of RPS15 26675346
2014-07-19 12:34:00 Study shows that ribosomal protein s15 is a key pathogenic LRRK2 substrate in Drosophila and human neuron Parkinson's disease models. 24725412

名称对应

Type IDs
Synonymous RIG, S15
Gene
UniProtKB-ID: RS15_HUMAN, K7ELC2_HUMAN
UniprotKB: P62841, K7ELC2
UniParc: UPI0000000EAF, UPI0000D4C6EE
EMBL: AF145025, J02984, BC105810, BC064908, BC141832, M32405, AC027307
Ensembl: ENSG00000115268
KO: hsa:6209
Nucleutide sequences
EMBL-CDS: AAP97277.1, AAI05811.1, AAA36036.1, AAA36568.1, AAH64908.1, AAI41833.1
Ensembl_TRS: ENST00000592588, ENST00000593052
Protein sequencees
Ensembl_PRO: ENSP00000467466, ENSP00000466010
RefSeq: NP_001295155.1, NP_001009.1
Others
UniRef100: UniRef100_P62841, UniRef100_K7ELC2
UniRef90: UniRef90_K7ELC2, UniRef90_P62841
UniRef50: UniRef50_O95996, UniRef50_Q9FY66
UniGene: Hs.406683
CCDS: CCDS12067.1

全选

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