| Type | Description |
|---|---|
| Definition | sialic acid binding Ig-like lectin 15 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:11:00 | Siglec-15 on Osteoclasts Is Crucial for Bone Erosion in Serum-Transfer Arthritis. | 33020147 |
| 2019-05-11 12:15:00 | Siglec-15 is a potential target for normalization cancer immunotherapy. | 30833750 |
| 2016-05-14 12:17:00 | Siglec-15 does not mediate joint destruction in inflammatory arthritis | 26027508 |
| 2015-08-24 01:04:00 | The present findings indicate that Siglec-15 is involved in estrogen deficiency-induced differentiation of osteoclasts and is thus a potential therapeutic target for postmenopausal osteoporosis. | 25460183 |
| 2014-06-28 12:12:00 | Siglec-15 regulates osteoclast development and bone resorption by modulating receptor activator of nuclear factor kappaB ligand (RANKL) signaling in association with DAP12. | 23677868 |
| Type | IDs |
|---|---|
| Synonymous | Cd33l3, EG620235, SIGLEC-I |
| Gene |
UniProtKB-ID:
A7E1W8_MOUSE
UniprotKB:
A7E1W8
UniParc:
UPI000159BC17
EMBL:
AY971517,
AC126553
Ensembl:
ENSMUSG00000091055
KO:
mmu:620235
|
| Nucleutide sequences |
EMBL-CDS:
AAY40744.1
Ensembl_TRS:
ENSMUST00000170760
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000126901
RefSeq:
XP_011245393.1,
XP_030106421.1,
NP_001094508.1,
XP_036017122.1
|
| Others |
UniRef100:
UniRef100_A7E1W8
UniRef90:
UniRef90_A7E1W8
UniRef50:
UniRef50_A7E1W8
UniGene:
Mm.35607
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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