Acap2 - ArfGAP with coiled-coil, ankyrin repeat and PH domains 2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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619382 Acap2

基因描述

Type	Description
Definition	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2

研究结论

Date	Results	Publications
2015-06-20 12:44:00	showed by knockdown-rescue approaches that neither a centaurin-beta2 binding-deficient Rab35(T76S/T81A) mutant nor a Rab35 binding-deficient centaurin-beta2(N610A/N691A) mutant supported neurite outgrowth of PC12 cells	25694427
2015-02-07 10:57:00	Rab35/ACAP2 and cytohesin-2 antagonistically control oligodendrocyte differentiation and myelination through Arf6 regulation.	24600047
2012-10-27 11:21:00	Rab35 regulates Arf6 activity through centaurin-beta2 (ACAP2) during neurite outgrowth.	22344257

名称对应

Type	IDs
Synonymous	Centb2, cnt-b2
Gene	UniProtKB-ID: ACAP2_RAT, A0A0G2K4T3_RAT UniprotKB: Q5FVC7, A0A0G2K4T3 UniParc: UPI00004C96AF, UPI0003D0C047 EMBL: BC090073, AC115456 Ensembl: ENSRNOG00000001730 KO: rno:619382
Nucleutide sequences	EMBL-CDS: AAH90073.1 Ensembl_TRS: ENSRNOT00000029549, ENSRNOT00000080834
Protein sequencees	Ensembl_PRO: ENSRNOP00000030250, ENSRNOP00000073162 RefSeq: XP_017453554.1, XP_017453556.1, NP_001029178.1, XP_006248553.1, XP_017459763.1, XP_006248551.1, XP_006248549.1, XP_017453555.1
Others	UniRef100: UniRef100_Q5FVC7, UniRef100_A0A0G2K4T3 UniRef90: UniRef90_Q5FVC7, UniRef90_A0A0G2K4T3 UniRef50: UniRef50_Q6IVG4, UniRef50_Q6ZQK5 UniGene: Rn.208307

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
25694427	Structure-function analyses of the small GTPase Rab35 and its effector protein centaurin-Î²2/ACAP2 during neurite outgrowth of PC12 cells. J Biol Chem Kan Etoh , Mitsunori Fukuda	2015-04-03	-
24600047	Rab35, acting through ACAP2 switching off Arf6, negatively regulates oligodendrocyte differentiation and myelination. Mol. Biol. Cell Yuki Miyamoto , Natsuki Yamamori , Tomohiro Torii , Akito Tanoue , Junji Yamauchi	2014-05-01	Rab35, Acap2, Arf6
23572513	Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth. J. Cell. Sci. Hotaka Kobayashi , Mitsunori Fukuda	2013-06-01	Arf6, Micall1, Rab35, Acap2, Rab35, Ehd1, Micall1, Acap2
22344257	Rab35 regulates Arf6 activity through centaurin-Î²2 (ACAP2) during neurite outgrowth. J. Cell. Sci. Hotaka Kobayashi , Mitsunori Fukuda	2012-05-01	Rab35, Acap2, Arf6
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
19946888	Defining the membrane proteome of NK cells. J Mass Spectrom Dhimankrishna Ghosh , Dustin Lippert , Oleg Krokhin , John P Cortens , John A Wilkins	2010-01-01	MED6, PDCD6IP, MED16, PIGK, DNAJB6, FARSB, DNM1L, ABCF2, HUWE1, ARPC3, ACTR3, ACTR2, RAD50, PREB, ACTR1B, LRPPRC, TRAP1, BCAP31, PLXNC1, LPCAT3, TNK2, PSME3, MPHOSPH9, FLOT1, DDX39A, AK6, ADAM10, PLIN3, CALCOCO2, CDK9, ABCC4, ZMPSTE24, AKAP8, BET1, MARCH6, KATNB1, ADAR, EMC8, BTN3A3, ATP8A1, NDC80, CDIPT, PGRMC2, TUBGCP3, ECI2, COG5, SLC25A17, LRRC41, SYNCRIP, MYBBP1A, DDX17, CHERP, HYOU1, IPO7, NOP56, ARL6IP5, HTATIP2, AGPAT1, ARFGEF2, RABAC1, SLU7, PRPF8, PAICS, CENPE, PMVK, KHDRBS1, CELF1, GNA13, CFL1, MGEA5, YME1L1, STAG2, CTSC, GIPC1, HBS1L, TUBGCP2, PGRMC1, MAN1A2, PNPLA6, MAGED2, ADCY3, EHD1, TOMM34, ERP29, YWHAQ, ASCC3, GCN1, IMMT, ILVBL, SLC27A4, SLC27A3, KIF2C, GLIPR1, CPSF6, DDX52, WWP2, CNTRL, CHD4, KRR1
12477932	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team	2002-12-24	-
11062263	ACAPs are arf6 GTPase-activating proteins that function in the cell periphery. J. Cell Biol. T R Jackson , F D Brown , Z Nie , K Miura , L Foroni , J Sun , V W Hsu , J G Donaldson , P A Randazzo	2000-10-30	-
11001876	Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. Biochem J S Dowler , R A Currie , D G Campbell , M Deak , G Kular , C P Downes , D R Alessi	2000-10-01	-

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