| Type | Description |
|---|---|
| Definition | ribophorin I |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:26:00 | Study provides evidence that Rpn1-Ser361 is a prevalent phosphosite that is required for proper assembly and activity of the 26S proteasome and identified multiple kinases, including PIM1/2/3, that can phosphorylate Rpn1-S361 and have demonstrated that UBLCP1 is a physiologically relevant phosphatase of this site. Blocking phosphorylation of Rpn1-S361 leads to slowed proliferation and mitochondrial dysfunction. | 31843888 |
| 2017-09-23 10:27:00 | These results clearly demonstrate that the association of malectin with ribophorin I is required to capture misfolded alpha1-antitrypsin and direct them to the degradation pathway. | 25451265 |
| 2013-01-26 10:21:00 | Data indicate that malectin functions by forming a complex with ribophorin I. | 22988243 |
| 2010-01-21 00:00:00 | ribophorin I can regulate the delivery of precursor proteins to the OST complex by capturing substrates and presenting them to the catalytic core. | 18607003 |
| 2009-09-20 21:32:00 | Observational study of gene-disease association. (HuGE Navigator) | 19064571 |
| Type | IDs |
|---|---|
| Synonymous | OST1, RBPH1 |
| Gene |
UniProtKB-ID:
RPN1_HUMAN
UniprotKB:
P04843
UniParc:
UPI00001338BA
EMBL:
CH471052,
CR749284,
AK312369,
Y00281,
BC010839
Ensembl:
ENSG00000163902
KO:
hsa:6184
|
| Nucleutide sequences |
EMBL-CDS:
EAW79307.1,
CAA68392.1,
AAH10839.1,
CAH18139.1,
EAW79308.1,
EAW79306.1,
BAG35287.1
Ensembl_TRS:
ENST00000296255
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000296255
RefSeq:
NP_002941.1
|
| Others |
UniRef100:
UniRef100_P04843
UniRef90:
UniRef90_P04843
UniRef50:
UniRef50_P04843
UniGene:
Hs.518244,
Hs.603636
CCDS:
CCDS3051.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员