| Type | Description |
|---|---|
| Definition | ribosomal protein L11 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-03 11:14:00 | patients with RPL11 mutations were less likely to need chronic treatment. Birth defects, including cardiac, skeletal, hand, cleft lip or palate and genitourinary malformations, also varied among the various genetic groups | 29044489 |
| 2018-02-24 10:35:00 | PICT-1 is a major nucleolar sensor of the DNA damage repair response and an important upstream regulator of p53 via the RPL11-MDM2-p53 pathway. | 27829214 |
| 2018-02-17 11:09:00 | A novel pathogenic mutation in RPL11 identified in a patient diagnosed with diamond Blackfan anemia as a young adult. | 27667165 |
| 2018-02-10 10:51:00 | RPL splicing variant is associated with Diamond-Blackfan anemia. | 28742285 |
| 2017-12-09 12:30:00 | Simulation of HEY1 Ser-68 phosphorylation prevents its interaction with p53, RPL11 and MDM2 and abolishes HEY1 migration to nucleolar caps upon ribosomal stress. Our findings uncover a novel mechanism for cross-talk between Notch signalling and nucleolar stress | 27129302 |
| Type | IDs |
|---|---|
| Synonymous | DBA7, GIG34, L11, uL5 |
| Gene |
UniProtKB-ID:
RL11_HUMAN,
Q5VVD0_HUMAN
UniprotKB:
P62913,
Q5VVD0
UniParc:
UPI00000019F7,
UPI0000071406
EMBL:
AB007171,
AF101385,
AF432212,
X79234,
CH471134,
BC018970,
AK311816,
L05092
Ensembl:
ENSG00000142676
KO:
hsa:6135
|
| Nucleutide sequences |
EMBL-CDS:
BAA25831.1,
CAA55816.1,
AAL99919.1,
AAD20460.3,
AAC15856.1,
AAH18970.1,
EAW95068.1,
BAG34759.1
Gene_ORFName:
hCG_1739238
Ensembl_TRS:
ENST00000374550,
ENST00000643754
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000496250,
ENSP00000363676
RefSeq:
NP_000966.2,
NP_001186731.1
|
| Others |
UniRef100:
UniRef100_P62913
UniRef90:
UniRef90_P62913
UniRef50:
UniRef50_P62913
UniGene:
Hs.719951
CCDS:
CCDS238.1,
CCDS85940.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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