| Type | Description |
|---|---|
| Definition | defensin alpha 1 and alpha 3, variable copy number locus |
| Date | Results | Publications |
|---|---|---|
| 2017-12-09 11:58:00 | Low alpha-defensin gene copy number increases the risk for IgA nephropathy and renal dysfunction | 27358498 |
| 2017-05-27 10:57:00 | we found that DEFA1A3 is expressed in renal epithelium and not restricted to myeloid-derived cells, such as neutrophils. In conclusion, low DEFA1A3 copy number associated with recurrent urinary tract infections in subjects in the RIVUR Study randomized to prophylactic antibiotics, providing evidence that copy number polymorphisms in an antimicrobial peptide associate with urinary tract infection risk | 26940096 |
| 2016-03-26 10:41:00 | RTD-1 reduced the secretion of tumor necrosis factor-alpha (TNF-alpha), interleukin (IL)-1beta, and IL-8 in lipopolysaccharide (LPS)-stimulated human blood monocytes and THP-1 macrophages | 26269197 |
| 2013-04-06 13:05:00 | DEFA1A3 copy numbers did not differ significantly between systemic lupus erythematosus patients and controls. DEFA1A3 copy numbers ranged from 3 to 11 in Han Chinese in Beijing and 4 to 16 in Japanese in Tokyo. | 23333728 |
| 2012-01-28 11:12:00 | a high DEFA1A3 copy number might be important in hindering the normal inflammatory response in CD, particularly colonic CD. | 21701837 |
| Type | IDs |
|---|---|
| Synonymous | DEFA1, DEFA3, DEFT1P |