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6128 RPL6

6128

RPL6

ribosomal protein L6

protein-coding

Homo sapiens

基因描述

Type Description
Definition ribosomal protein L6

研究结论

Date Results Publications
2020-09-19 11:41:00 60S ribosomal proteins L6 (RPL6) and RPL28, which are adjacent on the ribosome, play opposite roles in generating an influenza A virus-encoded peptide. Depleting RPL6 decreases ubiquitin-dependent peptide presentation, whereas depleting RPL28 increases ubiquitin-dependent and -independent peptide presentation. 30712990
2014-04-19 10:11:00 The ribosomal protein L6 binds to and suppresses the E3 ubiquitin ligase activity of HDM2, and subsequently attenuates HDM2-mediated p53 polyubiquitination and degradation. 24174547
2012-04-07 12:12:00 Down-regulation of RPL6 could suppress cell growth and cell cycle progression at least through down-regulating cyclin E 22043320
2010-05-03 11:06:00 RPL6 was overexpressed in human gastric cancer and its over-expression could promote cell growth and cell cycle progression at least through upregulating cyclin E expression. 20171175
2010-01-21 00:00:00 The high expression of RPL6/Taxreb107 in drug resistant gastric cancer cell shows its correlation with multiple-drug resistance in gastric cancer. 12678981

名称对应

Type IDs
Synonymous L6, SHUJUN-2, TAXREB107, TXREB1
Gene
UniProtKB-ID: RL6_HUMAN, Q8TBK5_HUMAN, A0A024RBK3_HUMAN
UniprotKB: Q02878, Q8TBK5, A0A024RBK3
UniParc: UPI000007039B, UPI0000001608
EMBL: CH471054, AB042820, D17554, BC071912, BC104826, BC004138, BC020679, S71022, BC104824, BC032299, X69391, BC022444
Ensembl: ENSG00000089009
KO: hsa:6128
Nucleutide sequences
EMBL-CDS: AAH71912.1, AAI04825.1, BAB17292.1, CAA49188.1, AAH04138.1, BAA04491.1, AAI04827.1, AAH20679.1, AAH32299.1, AAB30819.1, AAH22444.1, EAW98008.1, EAW98009.1, EAW98005.1, EAW98007.1, EAW98006.1, EAW98010.1
Gene_ORFName: hCG_38537
Ensembl_TRS: ENST00000424576, ENST00000202773
Protein sequencees
Ensembl_PRO: ENSP00000202773, ENSP00000403172
RefSeq: NP_001019833.1, NP_001307066.1, NP_001307067.1, NP_001307068.1, XP_016875270.1, NP_001307070.1, NP_001307071.1, NP_001307069.1, XP_016875271.1, NP_000961.2
Others
UniRef100: UniRef100_Q02878, UniRef100_Q8TBK5
UniRef90: UniRef90_Q02878
UniRef50: UniRef50_Q02878
UniGene: Hs.546283, Hs.744897
CCDS: CCDS9162.1

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