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610 HCN2

610

HCN2

hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

研究结论

Date Results Publications
2020-09-19 16:26:00 Effects of HCN2 Mutations on Dendritic Excitability and Synaptic Plasticity: A Computational Study. 31682955
2020-02-22 12:10:00 overexpression of TBX3 and HCN2 could reprogram human-induced pluripotent stem cells-derived cardiomyocytes into pacemaker-like cells 31916853
2019-05-25 11:42:00 No significant association was found between HCN1/HCN2 alleles, genotypes or haplotypes, and drug resistance in patients, however, it was suggested that HCN2 rs3752158 is involved in the susceptibility to juvenile myoclonic epilepsy. 29047147
2019-01-12 10:52:00 Data suggest that HCN2 variants can confer susceptibility to Genetic generalized epilepsy via a gain-of-function mechanism. 29064616
2017-11-18 12:40:00 beta2-adrenoceptors alone strongly enhanced the activity of HCN2 channels, and co-expression of odorant receptors further diversified the HCN2 channel activity. 29054409

名称对应

Type IDs
Synonymous BCNG-2, BCNG2, HAC-1
Gene
UniProtKB-ID: HCN2_HUMAN
UniprotKB: Q9UL51
UniParc: UPI000013CCF6
EMBL: AJ133733, AJ012582, AF065164, AJ133729, AC005559, AC004449, AJ133727, AJ133728, AF064877, AJ133731, AJ133734, AJ133730, AJ133732
Ensembl: ENSG00000099822
KO: hsa:610
Nucleutide sequences
EMBL-CDS: CAB42602.1, AAC33280.2, CAB42630.1, AAC39760.1, AAC28444.2
Ensembl_TRS: ENST00000251287
Protein sequencees
Ensembl_PRO: ENSP00000251287
RefSeq: NP_001185.3
Others
UniRef100: UniRef100_Q9UL51
UniRef90: UniRef90_Q9UL51
UniRef50: UniRef50_Q9UL51
UniGene: Hs.124161
CCDS: CCDS12035.1

全选

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