| Type | Description |
|---|---|
| Definition | eukaryotic elongation factor, selenocysteine-tRNA specific |
| Date | Results | Publications |
|---|---|---|
| 2018-09-29 10:18:00 | eEFSec employs a non-canonical mechanism involving the distinct C-terminal domain 4 for the release of the selenocysteinyl-tRNA during decoding on the ribosome | 27708257 |
| 2017-10-24 10:49:00 | EEFSEC, which encodes selenocysteine-tRNA specific eukaryotic elongation factor, participates in the incorporation of selenocysteine into selenoproteins. Selenoproteins serve critical cellular homeostatic functions in maintaining redox status and antioxidant defenses, as well as modulating inflammatory responses. These physiologic functions have been linked to the parturition process and preterm birth. | 28877031 |
| 2017-09-30 11:12:00 | In this genomewide association study, we found that variants at the EBF1, EEFSEC, AGTR2, WNT4, ADCY5, and RAP2C loci were associated with gestational duration and variants at the EBF1, EEFSEC, and AGTR2 loci with preterm birth. | 28877031 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20878950 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20877624 |
| Type | IDs |
|---|---|
| Synonymous | EFSEC, SELB |
| Gene |
UniProtKB-ID:
SELB_HUMAN
UniprotKB:
P57772
UniParc:
UPI000006DAE5,
UPI000013CE58
EMBL:
BC007933,
AL449214,
AF268872,
AL449210,
AL449217
Ensembl:
ENSG00000284869,
ENSG00000132394
KO:
hsa:60678
|
| Nucleutide sequences |
EMBL-CDS:
AAG13375.1,
AAH07933.1
Ensembl_TRS:
ENST00000644579,
ENST00000254730
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000254730,
ENSP00000494933
RefSeq:
XP_011511368.1,
XP_024309463.1,
XP_005247753.1,
XP_024309462.1,
NP_068756.2,
XP_024309464.1,
XP_024309461.1,
XP_024309460.1
|
| Others |
UniRef100:
UniRef100_P57772
UniRef90:
UniRef90_P57772
UniRef50:
UniRef50_P57772
UniGene:
Hs.477498
CCDS:
CCDS33849.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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