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60675 PROK2

60675

PROK2

prokineticin 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition prokineticin 2

研究结论

Date Results Publications
2021-03-28 19:06:00 Silencing PROK2 Inhibits Invasion of Human Cervical by Targeting MMP15 Expression. 32887509
2020-07-11 12:54:00 We demonstrated a significant upregulation of PROK2 levels in brain tissues of Abeta1-42 i.c.v. injected rats, transgenic AD mice (Tg2576), and in the hippocampus of AD patients. Additionally, through a pilot study, an approximate twofold increase of PROK2 levels has been proved in the serum of AD patients, compared to the control subjects, identifying a potential blood-based biomarker of the disease. 31766244
2019-11-30 10:14:00 In PK2-mediated anti-adipogenic signaling, KDM6A stabilizes and increases cytoplasmic beta-catenin levels to repress peroxisome proliferator-activated receptor-gamma expression and activity. Findings offer additional molecular targets to manipulate hEPDCs-involved tissue repair/regeneration in cardiometabolic and ischemic heart diseases. 29873146
2019-07-27 12:21:00 infiltrating neutrophils and 4T1 cells abundantly expressed prokineticin-2 (Prok2) and its receptor, Prokr1, respectively. Finally, the administration of 5-FU after the resection of the primary tumor failed to augment lung metastasis in the mice receiving Prokr1-deleted 4T1 cells. 29643149
2019-04-27 12:17:00 High PROK2 expression is associated with Glioma. 30803356

名称对应

Type IDs
Synonymous BV8, HH4, KAL4, MIT1, PK2
Gene
UniProtKB-ID: PROK2_HUMAN
UniprotKB: Q9HC23
UniParc: UPI000002B192, UPI0000132219
EMBL: AY349131, BC096695, AF333025, BC098110, BC069395, CH471055, AF182069, BC098162
Ensembl: ENSG00000163421
KO: hsa:60675
Nucleutide sequences
EMBL-CDS: AAK49919.1, AAG16893.2, AAH69395.1, AAH96695.1, AAR06657.1, EAW65506.1, AAH98162.1, AAH98110.1
Ensembl_TRS: ENST00000295619, ENST00000353065
Protein sequencees
Ensembl_PRO: ENSP00000295619, ENSP00000295618
RefSeq: NP_001119600.1, NP_068754.1, XP_016862463.1
Others
UniRef100: UniRef100_Q9HC23
UniRef90: UniRef90_Q9HC23
UniRef50: UniRef50_Q9HC23
UniGene: Hs.528665
CCDS: CCDS2916.1, CCDS46868.1

全选

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