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60673 ATG101

60673

ATG101

autophagy related 101

protein-coding

Homo sapiens

基因描述

Type Description
Definition autophagy related 101

研究结论

Date Results Publications
2019-10-26 12:14:00 The C-terminal deletion of ATG101 shows a significant defect in the interaction with PtdIns3K components and subsequently impairs autophagosome formation. This result clearly presents an additional role of ATG101 for bridging the ULK1 and PtdIns3K complexes in the mammalian autophagy process. 30081750
2016-07-30 11:05:00 Structure of the human Atg13-Atg101 HORMA heterodimer in the ULK1 complex that controls autophagy has been described. 26299944
2013-09-07 10:39:00 Data indicate mitogen lacritin stimulates FOXO3-ATG101 and FOXO1-ATG7 autophagic coupling and restores metabolic homeostasis. 23640897
2010-01-21 00:00:00 The identification of the novel protein, Atg101, and the validation of Atg13 and Atg101 as ULK1-interacting proteins, suggests an Atg1 complex is involved in the induction of macroautophagy in mammalian cells. 19287211
2010-01-21 00:00:00 These data suggest that Atg101 is a novel Atg protein that functions together with ULK, Atg13 and FIP200. 19597335

名称对应

Type IDs
Synonymous C12orf44
Gene
UniProtKB-ID: ATGA1_HUMAN, A0A024R128_HUMAN
UniprotKB: Q9BSB4, A0A024R128
UniParc: UPI000006DD29
EMBL: BC009937, AF218031, AK021835, BC005151, AC025259, CH471111
Ensembl: ENSG00000123395
KO: hsa:60673
Nucleutide sequences
EMBL-CDS: AAG17273.1, AAH09937.1, AAH05151.1, BAB13907.1, EAW58230.1, EAW58229.1
Gene_ORFName: PP894, hCG_37973
Ensembl_TRS: ENST00000336854
Protein sequencees
Ensembl_PRO: ENSP00000338990
RefSeq: NP_068753.2, NP_001092143.1, XP_024304888.1
Others
UniRef100: UniRef100_Q9BSB4
UniRef90: UniRef90_Q9BSB4
UniRef50: UniRef50_Q9BSB4
UniGene: Hs.9911
CCDS: CCDS8820.1

全选

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