Ppp2r2b - protein phosphatase 2, regulatory subunit B, beta-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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60660 Ppp2r2b

基因描述

Type	Description
Definition	protein phosphatase 2, regulatory subunit B, beta

研究结论

Date	Results	Publications
2011-02-03 14:32:00	Select PP2A heterotrimers oppose desensitization of the TrkA receptor tyrosine kinase, perhaps through dephosphorylation of inhibitory Ser/Thr phosphorylation sites on the receptor itself.	19029245
2010-01-21 00:00:00	spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit Bbeta2 antagonizes neuronal survival by promoting mitochondrial fission [SCA12]	18940801

名称对应

Type	IDs
Synonymous	Pppr2b2
Gene	UniProtKB-ID: 2ABB_RAT UniprotKB: P36877 UniParc: UPI000019A1BF, UPI0000124EA7 EMBL: BC078834, D38260, AY251277, D14421 Ensembl: ENSRNOG00000018851 KO: rno:60660
Nucleutide sequences	EMBL-CDS: BAA03313.1, AAH78834.1, AAP33142.1, BAA07412.1 Ensembl_TRS: ENSRNOT00000079585
Protein sequencees	Ensembl_PRO: ENSRNOP00000071824 RefSeq: XP_017456514.1, NP_071545.2, XP_017456518.1, XP_017456515.1, XP_017456517.1, XP_017456516.1
Others	UniRef100: UniRef100_P36877 UniRef90: UniRef90_P36877 UniRef50: UniRef50_P36877 UniGene: Rn.44437

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21746932	Induction of PP2A BÎ², a regulator of IL-2 deprivation-induced T-cell apoptosis, is deficient in systemic lupus erythematosus. Proc Natl Acad Sci U S A JosÃ© C CrispÃn , Sokratis A Apostolidis , Melissa I Finnell , George C Tsokos	2011-07-26	-
21471219	Mitochondrial dysfunction and oxidative stress contribute to the pathogenesis of spinocerebellar ataxia type 12 (SCA12). J Biol Chem Yu-Chun Wang , Chi-Mei Lee , Li-Ching Lee , Li-Chu Tung , Hsiu-Mei Hsieh-Li , Guey-Jen Lee-Chen , Ming-Tsan Su	2011-06-17	-
20669227	A genetic variant in a PP2A regulatory subunit encoded by the PPP2R2B gene associates with altered breast cancer risk and recurrence. Int J Cancer Alexei Vazquez , Diptee Kulkarni , Lukasz F Grochola , Gareth L Bond , Nicola Barnard , Deborah Toppmeyer , Arnold J Levine , Kim M Hirshfield	2011-05-15	-
21029765	Association between CAG repeat length in the PPP2R2B gene and Alzheimer disease in the Japanese population. Neurosci. Lett. Ryo Kimura , Takashi Morihara , Takashi Kudo , Kouzin Kamino , Masatoshi Takeda	2011-01-10	Ppp2r2b, PPP2R2B
20629122	Spinocerebellar ataxia type 12 identified in two Italian families may mimic sporadic ataxia. Mov Disord Alessandro Brussino , Claudio Graziano , Dario Giobbe , Marina Ferrone , Elisa Dragone , Carlo Arduino , Raffaele Lodi , Caterina Tonon , Anna Gabellini , Rita Rinaldi , Sara Miccoli , Enrico Grosso , Maria Cristina Bellati , Laura Orsi , Nicola Migone , Alfredo Brusco	2010-07-15	-
19029245	The protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiation. Mol. Cell. Biol. Michael J Van Kanegan , Stefan Strack	2009-02-01	Elk1, Hras, Ngf, Ntrk1, Ppp2ca, Ppp2r5d, Ppp2r5b, Map2k1, LOC100909468, LOC103694903, Map2k1, Ppp2r2d, Ppp2ca, Hras, Ppp2r5b, Ngf, Elk1, Ppp2r5d, Ntrk1, Ppp2r2b, Tfrc
18940801	The spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit Bbeta2 antagonizes neuronal survival by promoting mitochondrial fission. J Biol Chem Ruben K Dagda , Ronald A Merrill , J Thomas Cribbs , Yucui Chen , Johannes W Hell , Yuriy M Usachev , Stefan Strack	2008-12-26	-
15923182	Unfolding-resistant translocase targeting: a novel mechanism for outer mitochondrial membrane localization exemplified by the Bbeta2 regulatory subunit of protein phosphatase 2A. J Biol Chem Ruben K Dagda , Chris A Barwacz , J Thomas Cribbs , Stefan Strack	2005-07-22	-
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team	2004-10-01	Ldlrap1, Dnajc3, Rnaset2a, Btnl1, Isg15, Cyp3a41b, Ly6c2, Ccl21b, Eif3j2, Mup18, Lrrc19, Rcc1, 1700047I17Rik2, Pcsk9, Adat3, Tdrd7, Sco2, Gpr153, Pafah2, Gm44504, H6pd, Adprhl2, Gpn2, Rusc2, Stx12, Ppp1r8, Smpdl3b, Fam46b, Bsdc1, Slc44a1, Zfand2a, Rubcn, Kifc1, Pifo, C030017K20Rik, Cbarp, Rpl5, Micalcl, Atg14, Lrrc8c, Noc4l, Nsun5, Psph, Trrap, Mapre3, Ube3c, Tbc1d14, Hscb, Tyw1, Emilin1, Rab28, Pot1a, Parp11, Tada3, Tra2a, Brk1, Fbxl14, Phrf1, Plekha1, Gm21975, Ric8a, Mob2, Prkd2, Ccp110, Vrk3, Grwd1, Nlrp6, Trim68, Psip1, Spred3, Faap24, Ints4, Rrp8, Unc45a, Igflr1, Sf3b3, D8Ertd738e, Usb1, Champ1, Smim19, Exoc8, Gadd45gip1, Phkb, Dohh, Fam192a, Enkd1, Taf5l, Zdhhc7, Snapc2, Ak6, Gpat4, Dcun1d2, Ankrd10, Cog4, Hinfp, Lars2, Xylb, Imp3, Cmtm7

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