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6066 RNU2-1

6066

RNU2-1

RNA, U2 small nuclear 1

snRNA

Homo sapiens

基因描述

Type Description
Definition RNA, U2 small nuclear 1

研究结论

Date Results Publications
2020-07-18 11:30:00 We demonstrate that pseudouridylation levels in spliceosomal RNA U2 is dependent on the expression level of scaRNA1. Although further investigation is needed, we believe that scaRNA expression regulates biochemical modifications to spliceosomal RNAs, adjusting the fidelity of the spliceosome, allowing for controlled alternative splicing of mRNA that is important in embryonic development. 31953571
2016-12-17 10:04:00 suggest that the measurement of RNU2-1f detected in cerebrospinal fluid can be used as a diagnostic marker and also as a possible marker for treatment monitoring 26250566
2014-09-06 10:52:00 Data suggest that protein-protein interactions localize U2A' (SNRPA1) to the U2 snRNP (U2 small nuclear ribonucleoprotein) and exclude it from the U1 snRNP, rather than to enhance U2 snRNA (U2 small nuclear RNA; RNU2-1) binding of U2B'' (SNRPB2). 24866816
2014-08-30 12:09:00 Data suggest that the measurement of RNU2-1 fragments detected in the bile fluid can be used as a diagnostic marker for cholangiocarcinoma. 24482036
2013-09-21 10:43:00 RNU2-1 is a new bi-functional ncRNA that produces a 19-22nt fragment which may be useful in detecting lung cancer non-invasively in high risk patients. 23527303

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Type IDs
Synonymous RNU2, U2