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606496 Gsk3a

606496

Gsk3a

glycogen synthase kinase 3 alpha

protein-coding

Mus musculus

基因描述

Type Description
Definition glycogen synthase kinase 3 alpha

研究结论

Date Results Publications
2021-02-27 13:48:00 Phosphoproteomics and Bioinformatics Analyses Reveal Key Roles of GSK-3 and AKAP4 in Mouse Sperm Capacitation. 33023073
2020-07-18 11:18:00 These results suggest that GSK-3alpha acts as a fatty acids sensor in cardiomyocytes, stimulating lipid uptake and promoting its accumulation in cardiomyocytes through biased activation of PPARalpha, and that this process underlies the development of lipotoxic cardiomyopathy in obesity and diabetes. 30745182
2020-07-11 11:39:00 Interrelated functions of GSK3alpha and sperm PP2B are essential during epididymal sperm maturation and during fertilization. 31914663
2020-06-20 12:12:00 Cardiomyocyte-GSK-3alpha promotes mPTP opening and heart failure in mice with chronic pressure overload. 30928428
2020-06-06 13:32:00 Lentiviral shRNA knockdown of GSK3b, but not GSK3b, in the medial prefrontal cortex (mPFC) of WT mice also impaired Novel object recognition. CONCLUSION: These findings suggest that D3R acts via GSK3b signaling in the mPFC to play a functional role in Novel object recognition memory 31900153

名称对应

Type IDs
Synonymous 2700086H06Rik
Gene
UniProtKB-ID: GSK3A_MOUSE
UniprotKB: Q2NL51
UniParc: UPI00001C3B75
EMBL: BC111032, AC156992
Ensembl: ENSMUSG00000057177
KO: mmu:606496
Nucleutide sequences
EMBL-CDS: AAI11033.1
Ensembl_TRS: ENSMUST00000071739
Protein sequencees
Ensembl_PRO: ENSMUSP00000071654
RefSeq: XP_036009206.1, XP_006540321.1, NP_001026837.1, XP_006540322.1
Others
UniRef100: UniRef100_Q2NL51
UniRef90: UniRef90_Q2NL51
UniRef50: UniRef50_Q2NL51
UniGene: Mm.491101
CCDS: CCDS20976.1

全选

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研究热度

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