| Type | Description |
|---|---|
| Definition | glutamate metabotropic receptor 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:25:00 | Synaptic organisation and behaviour-dependent activity of mGluR8a-innervated GABAergic trilaminar cells projecting from the hippocampus to the subiculum. | 32016558 |
| 2019-10-12 11:23:00 | This study shows via knockdown of endogenous MEF2A in primary neuronal culture, that MEF2A is specifically required for Group I metabotropic glutamate receptor (mGluR)-mediated GluA2 internalisation, but does not regulate AMPAR expression or trafficking under basal conditions. | 29588465 |
| 2017-09-16 11:11:00 | Results show that group III mGluRs negatively modulate TRPA1 activity on cutaneous nociceptors. Furthermore, it is likely that this modulation occurs intracellularly at the level of the pathway. This study demonstrates that group III agonists may be effective in the treatment of mechanical hypersensitivity which can develop as a result of inflammation, nerve injury, chemotherapy and other disease states. | 27497709 |
| 2015-04-04 13:03:00 | Findings from the present study showed that trigeminal neurons express mGluR1alpha, mGluR2/3 and mGluR8, while SGCs only express mGluR1alpha and mGluR8. | 24495291 |
| 2015-01-31 11:59:00 | These results suggest that stimulation of mGluR8 inhibits thermoceptive responses and mechanical allodynia. | 24304862 |
| Type | IDs |
|---|---|
| Synonymous | Glur8, Gprc1h, Mglur8, mGluR8b, mGlur |
| Gene |
UniProtKB-ID:
GRM8_RAT,
F1LRA6_RAT
UniprotKB:
P70579,
F1LRA6
UniParc:
UPI0003D0FF87,
UPI000012F086
EMBL:
AC094900,
AC124918,
AC124785,
AC099466,
AC125643,
AC103101,
U63288,
AC095281
Ensembl:
ENSRNOG00000021468
KO:
rno:60590
|
| Nucleutide sequences |
EMBL-CDS:
AAB09537.1
Ensembl_TRS:
ENSRNOT00000031714
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000035953
RefSeq:
XP_017448348.1,
XP_017448346.1,
NP_071538.1,
XP_017448344.1,
XP_017448347.1,
XP_017448345.1
|
| Others |
UniRef100:
UniRef100_P70579,
UniRef100_F1LRA6
UniRef90:
UniRef90_P70579
UniRef50:
UniRef50_P70579
UniGene:
Rn.44420
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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