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605 BCL7A

605

BCL7A

BAF chromatin remodeling complex subunit BCL7A

protein-coding

Homo sapiens

基因描述

Type Description
Definition BAF chromatin remodeling complex subunit BCL7A

研究结论

Date Results Publications
2021-02-13 13:25:00 Frequent mutations in the amino-terminal domain of BCL7A impair its tumor suppressor role in DLBCL. 32576963
2019-09-07 10:11:00 Survival analysis showed that, compared with those who had higher levels of BCL7A expression, patients with ovarian cancer and low levels of BCL7A generally had shorter overall/relapse-free survival times. 31077237
2017-12-02 11:01:00 BCL7A, BRWD3, and AUTS2 demonstrate significantly higher mutation frequencies among AA cases. These genes are all involved in translocations in B-cell malignancies. Moreover, we detected a significant difference in mutation frequency of TP53 and IRF4 with frequencies higher among CA cases. Our study provides rationale for interrogating diverse tumor cohorts to best understand tumor genomics across populations. 29166413
2013-07-27 10:39:00 Data suggest that BCL7A may play an important role in cutaneous T-cell lymphoma (CTCL) carcinogenesis. 22856870
2013-05-11 12:40:00 Report describes BCL7A protein expression in normal lymphoid tissues and lymphomas using immunohistochemistry. 23043359

名称对应

Type IDs
Synonymous BCL7
Gene
UniProtKB-ID: BCL7A_HUMAN
UniprotKB: Q4VC05
UniParc: UPI0000519436, UPI000007304F
EMBL: AK296159, BC094723, AK316486, BC113627, CH471054, X89984
Ensembl: ENSG00000282873, ENSG00000110987
KO: hsa:605
Nucleutide sequences
EMBL-CDS: AAH94723.1, EAW98302.1, AAI13628.1, BAG58898.1, BAH14857.1, CAA62011.1
Ensembl_TRS: ENST00000261822, ENST00000538010, ENST00000635403, ENST00000635191
Protein sequencees
Ensembl_PRO: ENSP00000445868, ENSP00000489305, ENSP00000489010, ENSP00000261822
RefSeq: NP_001019979.1, NP_066273.1
Others
UniRef100: UniRef100_Q4VC05
UniRef90: UniRef90_Q4VC05
UniRef50: UniRef50_Q4VC05
UniGene: Hs.530970
CCDS: CCDS9226.1, CCDS53841.1

全选

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