| Type | Description |
|---|---|
| Definition | heparanase 2 (inactive) |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:18:00 | Heparanase-2 protects from LPS-mediated endothelial injury by inhibiting TLR4 signalling. | 31537875 |
| 2020-07-18 12:23:00 | Heparanase 2 and Urofacial Syndrome, a Genetic Neuropathy | 32274739 |
| 2020-07-18 12:23:00 | heparanase-2 functions as an inhibitor of the heparanase-1 enzyme and also inhibits neovascularization mediated by VEGF; the HPSE2 gene is repressed by the Polycomb complex, together suggesting a role as a tumor suppressor | 32274740 |
| 2020-07-18 12:23:00 | Opposing Effects of Heparanase and Heparanase-2 in Head & Neck Cancer | 32274741 |
| 2020-07-18 12:23:00 | gene cloning of HPSE2 | 32274738 |
| Type | IDs |
|---|---|
| Synonymous | HPA2, HPR2, UFS, UFS1 |
| Gene |
UniProtKB-ID:
HPSE2_HUMAN,
Q2M1H9_HUMAN
UniprotKB:
Q8WWQ2,
Q2M1H9
UniParc:
UPI000068429B,
UPI00001AFA63,
UPI00001AFB89,
UPI00001AEEC0,
UPI0000458942
EMBL:
AF282885,
AL356268,
AJ299719,
AF282886,
AL139243,
AL445251,
AL356220,
BC112356,
AL590036,
AJ299720,
AF282887
Ensembl:
ENSG00000172987
KO:
hsa:60495
|
| Nucleutide sequences |
EMBL-CDS:
AAG23421.1,
CAC82491.1,
AAG23423.1,
AAG23422.1,
CAC82492.1,
AAI12357.1
Ensembl_TRS:
ENST00000370549,
ENST00000370546,
ENST00000370552,
ENST00000628193
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000485916,
ENSP00000359580,
ENSP00000359577,
ENSP00000359583
RefSeq:
XP_011538331.1,
XP_011538332.1,
XP_024303887.1,
XP_016871987.1,
NP_068600.4,
XP_016871985.1,
XP_024303888.1,
NP_001159717.1,
XP_006718000.1,
XP_011538333.1,
XP_016871984.1,
NP_001159718.1,
NP_001159716.1,
XP_016871986.1
|
| Others |
UniRef100:
UniRef100_Q2M1H9,
UniRef100_Q8WWQ2
UniRef90:
UniRef90_Q8WWQ2
UniRef50:
UniRef50_Q8WWQ2
UniGene:
Hs.500750,
Hs.676960,
Hs.689544
CCDS:
CCDS53566.1,
CCDS53567.1,
CCDS53568.1,
CCDS7477.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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