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6049 RNF6

6049

RNF6

ring finger protein 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition ring finger protein 6

研究结论

Date Results Publications
2021-01-02 12:48:00 RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination. 31645658
2020-05-09 13:07:00 the oncogenic effect of RNF6 in hepatocellular carcinoma is partially dependent on FoxA1 degradation. 30496760
2020-02-15 13:11:00 downregulation of miR-26a-5p plays essential roles in breast cancer by mediating RNF6/ERalpha/Bcl-xL axis. 31063232
2019-09-28 11:41:00 Data suggest that targeting the ring finger 6 protein (RNF6)/protein-tyrosine phosphatase SHP-1 (SHP-1)/signal transducer and activator of transcription 3 axis provides a potential therapeutic option for RNF6-amplified tumors. 29288235
2019-07-06 11:02:00 RNF6-mediated ubiquitination and degradation of TLE3 activates the Wnt/beta-catenin pathway in colorectal carcinogenesis 29374067

名称对应

Type IDs
Gene
UniProtKB-ID: RNF6_HUMAN, A0A024RDP2_HUMAN, A0A0S2Z4G9_HUMAN
UniprotKB: Q9Y252, A0A024RDP2, A0A0S2Z4G9
UniParc: UPI0000073AEA, UPI0000E00F32, UPI00017A6D64, UPI0000000A0A
EMBL: AJ010346, AK293272, KU178310, AL138966, CH471075, AL133621, BC034688, KU178309, AF293342, AY009109, AK312435, AJ010347
Ensembl: ENSG00000127870
KO: hsa:6049
Nucleutide sequences
EMBL-CDS: BAG56801.1, AAH34688.1, CAB63747.1, AAG49400.1, CAB40414.1, CAB40413.1, AAK00848.1, BAG35344.1, EAX08380.1, ALQ33767.1, EAX08382.1, EAX08381.1, EAX08383.1, ALQ33768.1
Gene_ORFName: hCG_28217
Ensembl_TRS: ENST00000381588, ENST00000346166, ENST00000381570
Protein sequencees
Ensembl_PRO: ENSP00000371000, ENSP00000370982, ENSP00000342121
RefSeq: NP_898865.1, XP_016876175.1, NP_005968.1, XP_024305158.1, XP_024305160.1, NP_898864.1, XP_016876176.1, XP_005266543.1, XP_011533480.1, XP_024305159.1, XP_016876174.1, NP_898866.1, XP_011533479.1, XP_005266542.1
Others
UniRef100: UniRef100_Q9Y252, UniRef100_A0A0S2Z4G9
UniRef90: UniRef90_Q9Y252-3, UniRef90_Q9Y252
UniRef50: UniRef50_Q9Y252, UniRef50_Q9Y252-3
UniGene: Hs.136885
CCDS: CCDS9316.1

全选

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