| Type | Description |
|---|---|
| Definition | interferon inducible GTPase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:52:00 | Interferon-Inducible GTPase 1 Impedes the Dimerization of Rabies Virus Phosphoprotein and Restricts Viral Replication. | 32796066 |
| 2016-10-22 11:35:00 | The study determined the crystal structure of an oligomerization-impaired Irga6 mutant bound to a non-hydrolyzable GTP analog. | 26934976 |
| 2016-10-22 10:58:00 | These data identify Toxoplasma gondii GRA7 as a regulator for ROP18-specific inactivation of murine Irga6. | 26247512 |
| 2014-12-20 12:34:00 | ROP5 uses a highly polymorphic surface to bind adjacent to the nucleotide-binding domain of an IRG and that this produces a profound allosteric change in the IRGa6 structure. [Rop5] | 25118287 |
| 2012-11-24 10:41:00 | This study defines the catalytic G-domain interface by mutagenesis and presents a model of how GTP hydrolysis is activated in Irga6 complexes, based on the substrate-twinning reaction mechanism of the signal recognition particle and its receptor (SRalpha). | 21276251 |
| Type | IDs |
|---|---|
| Synonymous | 2900074L10Rik, AI046432, AW111922, Ifgga1, Iigp, Irga6 |
| Gene |
UniProtKB-ID:
IIGP1_MOUSE,
J7NNX8_MOUSE
UniprotKB:
Q9QZ85,
J7NNX8
UniParc:
UPI0000025937
EMBL:
AK153060,
AJ007971,
BC004649,
AF194871,
CT010300,
FR734016
Ensembl:
ENSMUSG00000054072
KO:
mmu:60440
|
| Nucleutide sequences |
EMBL-CDS:
CAA07798.1,
CAJ18508.1,
AAH04649.1,
AAF07195.1,
BAE31686.1,
CBY65979.1
Ensembl_TRS:
ENSMUST00000237185,
ENSMUST00000066912,
ENSMUST00000032473
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000063390,
ENSMUSP00000157568,
ENSMUSP00000032473
RefSeq:
XP_030106419.1,
XP_011245282.1,
XP_011245281.1,
NP_068564.4,
XP_030106417.1,
XP_011245280.1,
NP_001139747.1,
XP_036017120.1
|
| Others |
UniRef100:
UniRef100_Q9QZ85
UniRef90:
UniRef90_Q9QZ85
UniRef50:
UniRef50_Q9QZ85
UniGene:
Mm.261140
CCDS:
CCDS29270.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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