| Type | Description |
|---|---|
| Definition | MCL1, BCL2 family apoptosis regulator |
| Date | Results | Publications |
|---|---|---|
| 2020-01-11 12:09:00 | Fbw7 participates in oxidative stressinduced myocardial cell injury via interacting with Mcl1. | 31257502 |
| 2019-10-12 10:46:00 | roles of GSK3beta and MCL-1 in modulating high-glucose-induced cardiomyocyte apoptosis and maternal diabetes-induced abnormalities | 31197456 |
| 2018-02-24 10:59:00 | elevated miR-302 levels increased apoptosis-related protein levels and cardiomyocyte apoptosis, and luciferase reporter assays revealed miR-302 binding to the Mcl-1 mRNA 3' untranslated region. | 28491238 |
| 2017-04-08 10:15:00 | the results of the present study elucidated a novel mechanism by which miR153 regulates the survival of cardimyocytes during oxidative stress through the modulation of apoptosis and autophagy. These effects may be mediated directly by targeting Mcl1. | 27220418 |
| 2015-12-05 10:49:00 | findings indicated that OSM induces Mcl-1 expression via activation of ERK1/2, JAK1/2, and CREB; furthermore, OSM-mediated Mcl-1 induction contributes to bioenergetic improvements | 25986861 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MCL1_RAT
UniprotKB:
Q9Z1P3
UniParc:
UPI0000402748
EMBL:
BC078835,
AF115380,
AF144096
KO:
rno:60430
|
| Nucleutide sequences |
EMBL-CDS:
AAD13295.1,
AAH78835.1,
AAD31519.1
|
| Protein sequencees |
RefSeq:
NP_068618.2
|
| Others |
UniRef100:
UniRef100_Q9Z1P3
UniRef90:
UniRef90_P97287
UniRef50:
UniRef50_Q07820
UniGene:
Rn.129914,
Rn.161889
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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