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60422 Slc18a3

60422

Slc18a3

solute carrier family 18 member A3

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition solute carrier family 18 member A3

研究结论

Date Results Publications
2012-02-04 10:05:00 VACHT is inserted into the presynaptic membrane during synaptic vesicles' exocytosis, removed during their endocytotic recycling, and plays a role in non-quantal secretion of acetylcholine. 21557989
2010-01-21 00:00:00 During VAChT trafficking, the C-terminal dileucine-containing motif is sufficient as a dual signal for both internalization and synaptic vesicle targeting. 17451554
2010-01-21 00:00:00 A model for VAChT is suggested in which the known ion pair between lysine in transmembrane domain(TMD)II and aspartate in TMDXI controls the conformation or relative position of TMDXI, which in turn controls additional TMDs in the VAChT carboxy-terminal. 15924414
2010-01-21 00:00:00 results suggest that in rodent prefrontal cortex, the alpha7nAChR plays a major role in modulation of the postsynaptic excitation in spiny dendrites in contact with vesicular acetylcholine transporter containing axons 19374941
2010-01-21 00:00:00 These results made [125I]-( R,R)-5-AOIBV inferior to [125I]-IBVM for the VAChT exploration in vivo. 17998100

名称对应

Type IDs
Synonymous VACht, rVAT
Gene
UniProtKB-ID: VACHT_RAT
UniprotKB: Q62666
UniParc: UPI000015042B
EMBL: X80395, U09211, U09838
KO: rno:60422
Nucleutide sequences
EMBL-CDS: CAA56604.1, AAA20498.1, AAA50831.1
Protein sequencees
RefSeq: NP_113851.1
Others
UniRef100: UniRef100_Q62666
UniRef90: UniRef90_Q62666
UniRef50: UniRef50_Q16572
UniGene: Rn.9987

全选

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研究热度

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