| Type | Description |
|---|---|
| Definition | exocyst complex component 4 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-02 11:21:00 | Sec8 regulates N-cadherin expression by controlling Smad3 and Smad4 expression through CBP, thereby mediating the epithelial-mesenchymal transition. | 27769780 |
| 2016-12-17 10:11:00 | Sec8 regulate Bcl-2 and Mcl-1 expressions but not Bcl-xl in malignant peripheral nerve sheath tumor cells. | 26892009 |
| 2016-01-16 11:36:00 | Sec8 regulates histone-modifying proteins ATF2 and RNF20. | 26283729 |
| 2015-12-26 12:13:00 | Sec8 knockdown in HSC3 cells resulted in reduced expressions of PAK1 and PAK2 by upregulating Pirh2 and Siah1 expression, which inhibited the ERK or p38 MAPK signalling pathway and cytokeratin8 phosphorylation and cell migration. | 25725287 |
| 2015-01-31 12:20:00 | knockdown of Sec8 enhances the binding of JIP4 to MAPK kinase 4, thereby decreasing the phosphorylation of MAPK kinase 4, JNK, and p38. | 25244576 |
| Type | IDs |
|---|---|
| Synonymous | SEC8, SEC8L1, Sec8p |
| Gene |
UniProtKB-ID:
EXOC4_HUMAN,
Q6NX51_HUMAN
UniprotKB:
Q96A65,
Q6NX51
UniParc:
UPI000034ECA4,
UPI0000135758,
UPI000020FB10
EMBL:
AC024086,
AC009358,
AL834475,
AC009180,
AC007790,
AK022751,
AC083875,
BC067263,
AC009178,
CH236950,
AF132734,
AB051486,
AL831989,
CH471070,
AK027688,
AC083872,
AC093147,
AF380839
Ensembl:
ENSG00000131558
KO:
hsa:60412
|
| Nucleutide sequences |
EMBL-CDS:
BAB55298.1,
BAB14225.1,
EAW83804.1,
CAD39134.1,
AAK57456.1,
EAL24073.1,
BAB21790.1,
AAF66445.1,
CAD89977.1,
AAH67263.1
Ensembl_TRS:
ENST00000393161,
ENST00000253861
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000376868,
ENSP00000253861
RefSeq:
XP_016867983.1,
NP_068579.3,
NP_001032203.1,
XP_005250580.1
|
| Others |
UniRef100:
UniRef100_Q6NX51,
UniRef100_Q96A65
UniRef90:
UniRef90_Q62824
UniRef50:
UniRef50_Q62824
UniGene:
Hs.321273
CCDS:
CCDS5829.1,
CCDS43648.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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