| Type | Description |
|---|---|
| Definition | transient receptor potential cation channel, subfamily C, member 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 10:33:00 | We demonstrate that TRPC3-NFATc3 signaling is modulated by P.E. and critically regulates ventricular CF phenotype and MF. These findings strongly argue for P.E., through TRPC3 targeting, as potential and interesting therapeutics for MF management. | 30318928 |
| 2019-01-05 10:45:00 | Pharmacologically attenuating endogenous activation of TRPM4, TRPC3, or Ca(2+)-activated nonselective cation current in vitro similarly reduced the amplitude of inspiratory motoneuronal activity without significant perturbations of inspiratory frequency or variability of the rhythm. Amplitude perturbations were correlated with reduced inspiratory glutamatergic pre-Botzinger complex neuronal activity. | 29435486 |
| 2018-10-27 10:42:00 | Inhibition of TRPC3 suppressed intracellular Ca(2+) levels in hyperthermia-treated hippocampal neuronal cells | 29748835 |
| 2018-07-28 10:05:00 | In the trigeminal ganglion (TG), 56.1, 84.1, and 68.3% of sensory neurons were immunoreactive (IR) for TRPC1, TRPC3, and TRPC4, respectively. | 28697491 |
| 2018-05-19 10:12:00 | Findings indicate that PI3K/AKT may be common down-stream molecules for TRPC3- and ETB receptor signaling pathways during vasogenic edema formation. In addition, the present data demonstrate for the first time that TRPC3 may integrate VEGF- and NFkappaB-mediated vasogenic edema formation following SE. | 28764936 |
| Type | IDs |
|---|---|
| Synonymous | TrpC3c, Trrp3 |
| Gene |
UniProtKB-ID:
F1LNQ7_RAT
UniprotKB:
F1LNQ7
UniParc:
UPI000154F350
EMBL:
CH473961,
AC116283
Ensembl:
ENSRNOG00000016070
KO:
rno:60395
|
| Nucleutide sequences |
EMBL-CDS:
EDM01287.1
Gene_ORFName:
rCG_41547
Ensembl_TRS:
ENSRNOT00000046700
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000046270
RefSeq:
XP_017446552.1,
XP_008759163.1,
XP_006232344.2,
XP_017446553.1,
NP_068539.2
|
| Others |
UniRef100:
UniRef100_F1LNQ7
UniRef90:
UniRef90_Q13507
UniRef50:
UniRef50_Q13507
UniGene:
Rn.45385
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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