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60365 Rbm8a

60365

Rbm8a

RNA binding motif protein 8a

protein-coding

Mus musculus

基因描述

Type Description
Definition RNA binding motif protein 8a

研究结论

Date Results Publications
2018-03-10 10:23:00 our data demonstrate that miR-29a regulates the proliferation and differentiation of RPCs by directly targeting Rbm8a, providing us with a better understanding of the molecular mechanisms that govern RPC proliferation and differentiation. 28404883
2017-11-25 14:10:00 Data suggest that, in embryonic stem cells, Gsk3b/Gsk3a phosphorylate splicing factors (Rbm8a, Srsf9, and Psf) and nucleolar proteins (Npm1 and Phf6); Gsk3b/Gsk3a are key to alternative splicing of close to 190 genes. (Gsk3 = glycogen synthase kinase-3; Rbm8a = RNA binding motif protein 8a; Srsf9 = splicing factor, arginine-serine-rich 9; Psf = replication protein Psf; Npm1 = nucleophosmin 1; Phf6 = PHD finger protein 6) 28916722
2017-05-27 10:25:00 we first show that Eif4a3 haploinsufficiency phenocopies aberrant neurogenesis and microcephaly of Magoh and Rbm8a mutant mice.we show that genetic ablation of one downstream pathway, p53, significantly rescues microcephaly of all 3 EJC mutant 27618312
2016-05-14 11:08:00 this data suggests a novel role of RBM8a in the regulation of neurodevelopment. 26094033
2014-03-01 12:17:00 This is the first study that demonstrates the key role of RBM8a on the emotional behaviors in mice. 23638902

名称对应

Type IDs
Synonymous 2310057C03Rik, AA673428, Rbm8
Gene
UniProtKB-ID: RBM8A_MOUSE
UniprotKB: Q9CWZ3
UniParc: UPI00000272BF, UPI0000004160
EMBL: BC058376, BC020086, AK009953, AK139805, BC132653, KF051021, AC122037, BC132651, CH466620, AK082925, AK010284
Ensembl: ENSMUSG00000038374
KO: mmu:60365
Nucleutide sequences
EMBL-CDS: EDL38900.1, AHX83807.1, AAH20086.1, AAI32652.1, BAB26605.1, AAI32654.1, BAE24142.1, BAC38693.1, AAH58376.1, BAB26820.1
Ensembl_TRS: ENSMUST00000048915, ENSMUST00000196456
Protein sequencees
Ensembl_PRO: ENSMUSP00000044548, ENSMUSP00000143190
RefSeq: NP_001095877.1, NP_080151.2
Others
UniRef100: UniRef100_Q9Y5S9
UniRef90: UniRef90_Q9Y5S9
UniRef50: UniRef50_Q9Y5S9
UniGene: Mm.261972
CCDS: CCDS51005.1, CCDS79983.1

全选

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