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6035 RNASE1

6035

RNASE1

ribonuclease A family member 1, pancreatic

protein-coding

Homo sapiens

基因描述

Type Description
Definition ribonuclease A family member 1, pancreatic

研究结论

Date Results Publications
2020-09-26 13:08:00 Processing by RNase 1 forms tRNA halves and distinct Y RNA fragments in the extracellular environment. 32609822
2020-06-06 13:41:00 Chromatin immunoprecipitation kinetics revealed that HDAC2 accumulates at the RNASE1 promoter upon TNF-alpha stimulation, indicating an essential role for HDAC2 in regulating RNase1 expression. Thus, proinflammatory stimulation induced recruitment of HDAC2 to attenuate histone acetylation at the RNASE1 promoter site. 31039328
2019-11-30 12:18:00 N-glycosylation of human RNase 1 improves its resistance to both thermal denaturation and proteolytic degradation but reduces its catalytic activity.N-glycosylation of Asn34 in human RNase 1 significantly improves overall protein stability while maintaining robust catalytic activity. 30633504
2017-06-03 12:39:00 Data suggest that ribonuclease inhibitor (RNH1) protects HeLa cells from ribonuclease 1 (RNase 1). 27806571
2015-10-31 10:37:00 Focusing on the increase in an N-glycosylated Asn residue of serum pancreatic ribonuclease 1, specifically Asn(88), affords a new diagnostic marker for pancreatic cancer 25336120

名称对应

Type IDs
Synonymous RAC1, RIB1, RNS1
Gene
UniProtKB-ID: RNAS1_HUMAN, W0UV93_HUMAN
UniprotKB: P07998, W0UV93
UniParc: UPI000013448E
EMBL: CH471078, HG328837, CR450318, BC022882, S79281, X79235, AK312100, BC005324, X62946, D26129, DQ494867
Ensembl: ENSG00000129538
KO: hsa:6035
Nucleutide sequences
EMBL-CDS: BAA05124.1, AAH05324.1, CAA55817.1, AAB35096.1, EAW66438.1, BAG35036.1, ABF00144.1, EAW66437.1, CAA44718.1, CAG29314.1, AAH22882.1, CDG31913.1
Ensembl_TRS: ENST00000397967, ENST00000340900, ENST00000412779, ENST00000397970
Protein sequencees
Ensembl_PRO: ENSP00000399493, ENSP00000344193, ENSP00000381057, ENSP00000381060
RefSeq: NP_002924.1, NP_937875.1, NP_937877.1, NP_937878.1
Others
UniRef100: UniRef100_P07998
UniRef90: UniRef90_P07998
UniRef50: UniRef50_P07998
UniGene: Hs.78224
CCDS: CCDS9559.1

全选

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