| Type | Description |
|---|---|
| Definition | relaxin 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:15:00 | Tissue-specific relaxin-2 is differentially associated with the presence/size of an arterial aneurysm and the severity of atherosclerotic disease in humans. | 32024951 |
| 2020-06-27 10:18:00 | Investigated the potential beneficial effects and mechanisms of relaxin-2 on livers of two mouse models: high-fat diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD) with simple steatosis, and methionine-choline-deficient (MCD) diet-induced non-alcoholic steatohepatitis (NASH). | 30918325 |
| 2020-02-22 12:12:00 | The relaxin-2 mRNA and protein expression levels are decreased in the chronic rhinosinusitis with nasal polyps (CRSwNP) group compared with the chronic rhinosinusitis without nasal polyps (CRSsNP) group. The levels of TGF-beta1, collagen I, pSmad2/Smad3, Smad2, and Smad3 are decreased after relaxin-2 treatment ex vivo. However, relaxin-2, collagen I, pSmad2/Smad3, Smad2, and Smad3 levels are increased after TGF-beta1 t... | 31007042 |
| 2019-08-03 10:45:00 | This work represents an advance in biomedical science because it shows that serum relaxin-2 could discriminate prostate cancer patients from healthy or BPH controls, so may represent a novel prognostic and diagnostic markers for prostate cancer | 29513121 |
| 2019-04-27 11:22:00 | This study demonstrates the involvement of ADAM10 and PI3K/Akt signaling in mediating RLX-induced Notch-1 activation. | 29180109 |
| Type | IDs |
|---|---|
| Synonymous | H2, H2-RLX, RLXH2, bA12D24.1.1, bA12D24.1.2 |
| Gene |
UniProtKB-ID:
REL2_HUMAN
UniprotKB:
P04090
UniParc:
UPI000002B235,
UPI000002C1A0
EMBL:
AL135786,
BC126419,
S83200,
AF104935,
X00948,
BC126415
Ensembl:
ENSG00000107014
KO:
hsa:6019
|
| Nucleutide sequences |
EMBL-CDS:
CAA25460.1,
AAD14429.1,
AAI26416.1,
AAD21961.1,
AAI26420.1
Ensembl_TRS:
ENST00000381627
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000371040
RefSeq:
XP_024303414.1,
NP_001316120.1,
NP_604390.1,
NP_005050.2,
XP_024303415.1
|
| Others |
UniRef100:
UniRef100_P04090
UniRef90:
UniRef90_P04090
UniRef50:
UniRef50_P04090
UniGene:
Hs.127032
CCDS:
CCDS6460.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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