| Type | Description |
|---|---|
| Definition | G protein-coupled receptor kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-10 12:58:00 | Wide-field true-colour imaging and clinical characterization of a novel GRK1 mutation in Oguchi disease. | 32146548 |
| 2018-06-30 10:58:00 | In conclusion, in the present report, a novel missense mutation in GRK1 gene in homozygous state was reported in an Italian patient affected with Oguchi disease. | 28511019 |
| 2017-04-08 10:52:00 | Gene analysis determined a novel GRK1 mutation c.923T>C, which caused Oguchi disease in all siblings. This mutation, was demonstrated by amino acid alignment analysis to be in a phylogenetically conserved region and resulted in an amino acid change from leucine to proline at position 308. Thus, the present study reports a novel missense mutation of GRK1 in the affected members of a consanguineous Turkish family. | 27511724 |
| 2016-12-31 12:00:00 | AAMP Regulates Endothelial Cell Migration and Angiogenesis Through RhoA/Rho Kinase Signaling. | 26350504 |
| 2015-10-24 10:29:00 | In the Ca(2+)/NCS-1.D2R peptide complex, the C-terminal region adopts a 310 helix-turn-310 helix, whereas in the GRK1 peptide complex it forms an a-helix | 25979333 |
| Type | IDs |
|---|---|
| Synonymous | GPRK1, RHOK, RK |
| Gene |
UniProtKB-ID:
GRK1_HUMAN
UniprotKB:
Q15835
UniParc:
UPI0000133B08
EMBL:
L77497,
L77500,
L77498,
L77502,
AC187648,
L77501,
L77499,
AK289912,
L77496,
U63973,
L77503
Ensembl:
ENSG00000185974,
ENSG00000288263
KO:
hsa:6011
|
| Nucleutide sequences |
EMBL-CDS:
AAB05929.1,
AAT00534.2,
AAG50439.1,
BAF82601.1
Ensembl_TRS:
ENST00000335678,
ENST00000672946
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000499886,
ENSP00000334876
RefSeq:
XP_016876173.1,
NP_002920.1
|
| Others |
UniRef100:
UniRef100_Q15835
UniRef90:
UniRef90_Q15835
UniRef50:
UniRef50_Q15835
UniGene:
Hs.103501,
Hs.721727
CCDS:
CCDS81785.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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