| Type | Description |
|---|---|
| Definition | Ras homolog, mTORC1 binding |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:04:00 | Structural insights into TSC complex assembly and GAP activity on Rheb. | 33436626 |
| 2020-12-19 13:40:00 | Upregulation of Neuronal Rheb(S16H) for Hippocampal Protection in the Adult Brain. | 32188096 |
| 2020-12-05 12:58:00 | Phenome-Wide Scan Finds Potential Orofacial Risk Markers for Cancer. | 32184411 |
| 2020-08-29 12:45:00 | Silencing of RHEB inhibits cell proliferation and promotes apoptosis in colorectal cancer cells via inhibition of the mTOR signaling pathway. | 31332784 |
| 2020-06-27 11:45:00 | These results demonstrate that brain somatic mutations in RHEB are also responsible for the pathogenesis of Focal cortical dysplasia type II (FCDII), indicating that aberrant activation of mTOR signaling is a primary driver and potential drug target for FCDII. | 31337748 |
| Type | IDs |
|---|---|
| Synonymous | RHEB2 |
| Gene |
UniProtKB-ID:
RHEB_HUMAN,
A0A090N900_HUMAN
UniprotKB:
Q15382,
A0A090N900
UniParc:
UPI0000133863
EMBL:
AACC02000108,
AF493921,
D78132,
CH471173,
BC016155,
BC107705,
BT006958,
AK125446,
AF148645,
AC005996,
Z29677
Ensembl:
ENSG00000106615
KO:
hsa:6009
|
| Nucleutide sequences |
EMBL-CDS:
AAF73125.1,
AAI07706.1,
EAW53989.1,
AAM12635.1,
BAG54198.1,
BAA11211.1,
CAA82774.1,
AAP35604.1,
AAD15548.1,
AAH16155.1,
EAW53988.1,
EAL24515.1
Gene_ORFName:
tcag7.909,
hCG_19586
Ensembl_TRS:
ENST00000262187
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000262187
RefSeq:
NP_005605.1,
XP_011514759.1,
XP_024302622.1
|
| Others |
UniRef100:
UniRef100_Q15382
UniRef90:
UniRef90_Q15382
UniRef50:
UniRef50_Q15382
UniGene:
Hs.283521,
Hs.568850,
Hs.647068
CCDS:
CCDS5927.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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