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6002 RGS12

6002

RGS12

regulator of G protein signaling 12

protein-coding

Homo sapiens

基因描述

Type Description
Definition regulator of G protein signaling 12

研究结论

Date Results Publications
2017-09-30 13:38:00 Findings identify RGS12 as a candidate tumor-suppressor gene in AA prostate cancer, which acts by decreasing expression of AKT and MNX1, establishing a novel oncogenic axis in this disparate disease setting. 28611045
2017-05-20 14:31:00 Data support the notion that the Galpha, but not Gbetagamma, arm of the Gi/o signalling is involved in TRPC4 activation and unveil new roles for RGS and RGS12 in fine-tuning TRPC4 activities. 26987813
2010-09-15 22:06:00 Observational study of gene-disease association. (HuGE Navigator) 20627871
2010-04-07 21:40:00 Observational study of gene-disease association. (HuGE Navigator) 20198315
2010-01-21 00:00:00 RGS12 is essential for the terminal differentiation of osteoclasts induced by RANKL. 17042716

名称对应

Type IDs
Gene
UniProtKB-ID: RGS12_HUMAN
UniprotKB: O14924
UniParc: UPI000002B264, UPI000002B262, UPI0000133830, UPI0001915209, UPI00035BEEF2, UPI0000073237, UPI000002B263
EMBL: CH471131, AF030110, AL590235, AL645949, AF030143, AK301510, AF030140, AF030148, AF030142, AF464737, AF030134, AF030137, AF030147, AF030112, AF030149, AF030111, AF035152, BC118594, AF030109, AF030139, AF030145, AF030141, AF030151, AF030146, AF030144, AF030152, AF030138, AF030135, AF030136
Ensembl: ENSG00000159788
KO: hsa:6002
Nucleutide sequences
EMBL-CDS: AAB96645.1, AAB84187.1, EAW82470.1, AAB96644.1, BAH13500.1, AAB84186.1, AAB96646.1, EAW82468.1, AAB84114.1, EAW82465.1, AAI18595.1, AAL69961.1, AAB84007.1, AAC39835.1, EAW82469.1
Ensembl_TRS: ENST00000382788, ENST00000338806, ENST00000336727, ENST00000344733
Protein sequencees
Ensembl_PRO: ENSP00000372238, ENSP00000342133, ENSP00000339381, ENSP00000338509
RefSeq: XP_016864018.1, XP_016864020.1, XP_006713970.1, NP_937870.1, XP_016864021.1, XP_016864023.1, XP_006713968.1, XP_011511845.1, XP_016864019.1, NP_002917.1, XP_006713969.1, XP_016864022.1, NP_937872.1
Others
UniRef100: UniRef100_O14924
UniRef90: UniRef90_O14924
UniRef50: UniRef50_O14924
UniGene: Hs.527061
CCDS: CCDS3367.1, CCDS3368.1, CCDS3366.1

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