| Type | Description |
|---|---|
| Definition | regulator of G protein signaling 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:29:00 | N-Terminal Targeting of Regulator of G Protein Signaling Protein 2 for F-Box Only Protein 44-Mediated Proteasomal Degradation. | 33008920 |
| 2020-09-12 16:05:00 | RGS2 is prognostic for development of castration resistance and cancer-specific survival in castration-resistant prostate cancer. | 32449815 |
| 2019-11-02 10:54:00 | Study found downregulated RGS2 expression in early low grade prostate cancer (PC) which was caused by hypoxia. Its knockdown induced epithelial features and impaired metastatic properties. High RGS2 levels in advanced PC were correlated to poor survival and a metastatic status. This study describes new roles for RGS2 during PC progression and prognostic potential discriminating the indolent from metastatic forms. | 30467386 |
| 2019-07-13 12:45:00 | Low RGS2 expression due to DNA hypermethylation is associated with inflammation in cystic fibrosis. | 29944393 |
| 2019-04-06 12:49:00 | Interplay between negative and positive design elements in Galpha helical domains of G proteins determines interaction specificity toward RGS2. | 29925530 |
| Type | IDs |
|---|---|
| Synonymous | G0S8 |
| Gene |
UniProtKB-ID:
RGS2_HUMAN,
A0A024R939_HUMAN
UniprotKB:
P41220,
A0A024R939
UniParc:
UPI00020B16F6,
UPI00020B16F5,
UPI0000044575,
UPI00020B16F4
EMBL:
BT007065,
AL035407,
L13391,
AK313668,
CR457410,
CH471067,
AY971351,
BC007049,
L13463,
AF493926
Ensembl:
ENSG00000116741
KO:
hsa:5997
|
| Nucleutide sequences |
EMBL-CDS:
AAY40361.1,
AAC37587.1,
AAA20680.1,
AAP35728.1,
BAG36420.1,
AAH07049.1,
AAM12640.1,
EAW91231.1,
CAG33691.1,
EAW91232.1
Gene_ORFName:
GIG31,
hCG_41052
Ensembl_TRS:
ENST00000235382
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000235382
RefSeq:
NP_002914.1
|
| Others |
UniRef100:
UniRef100_P41220
UniRef90:
UniRef90_P41220
UniRef50:
UniRef50_P41220
UniGene:
Hs.78944
CCDS:
CCDS1377.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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