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5989 RFX1

5989

RFX1

regulatory factor X1

protein-coding

Homo sapiens

基因描述

Type Description
Definition regulatory factor X1

研究结论

Date Results Publications
2019-11-09 10:25:00 the recruitment of PP1c to promoters may be a mechanism by which RFX1 regulates the target genes. 30654936
2019-08-24 13:02:00 Results show that RFX1 expression deficiency leads to the overexpression of TLR4 and the activation of CD14(+) monocytes in coronary artery disease (CAD) patients by regulating DNA methylation and histone modifications, which highlights the vital role of RFX1 in the pathogenesis of CAD. 30857550
2018-11-17 11:02:00 RFX1 interacts with the D sequence of adeno-associated virus inverted terminal repeat and regulates AAV transduction. 29317724
2018-07-14 10:09:00 RFX1 expression was significantly lower in HCC tissues compared to the corresponding non-tumor tissues. In vitro studies suggested that knocking down RFX1 facilitated HCC cell invasion, while overexpression of RFX1 reduced the invasion of HCC cells. RFX1 regulated expression of some epithelial-mesenchymal transition markers. 29764705
2018-03-17 12:10:00 Findings indicate that RFX1 functions downstream of and phosphorylated duanyu18133 can inhibit RFX1 expression and suggest a unique role for RFX1 in Th17-related autoimmune diseases. 29422534

名称对应

Type IDs
Synonymous EFC, RFX
Gene
UniProtKB-ID: RFX1_HUMAN
UniprotKB: P22670
UniParc: UPI000013CE29
EMBL: AC020916, AC022098, BC049826, X58964
Ensembl: ENSG00000288283, ENSG00000132005
KO: hsa:5989
Nucleutide sequences
EMBL-CDS: AAH49826.1, CAA41730.1
Ensembl_TRS: ENST00000254325, ENST00000672295
Protein sequencees
Ensembl_PRO: ENSP00000500760, ENSP00000254325
RefSeq: XP_011526468.1, XP_011526470.1, XP_011526471.1, XP_011526469.1, NP_002909.4, XP_011526472.1, XP_011526467.1
Others
UniRef100: UniRef100_P22670
UniRef90: UniRef90_P22670
UniRef50: UniRef50_P22670
UniGene: Hs.655215
CCDS: CCDS12301.1

全选

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