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5983 RFC3

5983

RFC3

replication factor C subunit 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition replication factor C subunit 3

研究结论

Date Results Publications
2020-04-18 11:31:00 Ectopic expression of RFC3 induced epithelialmesenchymal transition (EMT), as determined by downregulation of Ecadherin, and upregulation of Ncadherin, vimentin and Wnt signaling target genes, including cMYC, Wnt1 and betacatenin, and the ratio of phosphorylatedglycogen synthase kinase 3 (GSK3)beta (Ser9)/GSK3beta. 31661124
2016-09-10 11:24:00 The expression level of RFC3 was markedly upregulated in the HCC tissues and cells. 26397132
2016-08-06 10:40:00 The expression level of RFC3 was remarkably up-regulated in ovarian cancer OVCAR-3 cells. Down-regulation of RFC3 expression arrested the cell cycle of OVCAR-3 cell in the S-phase and induced apoptosis. 26464638
2015-08-29 10:53:00 High RFC3 expression is associated with neoplastic myelopoiesis. 25541153
2015-01-10 10:19:00 our findings suggest that RFC3 protein is an important and independent biomarker with prognostic implications for patients with ovarian carcinoma. 25030735

名称对应

Type IDs
Synonymous RFC38
Gene
UniProtKB-ID: RFC3_HUMAN, A0A024RDQ8_HUMAN
UniprotKB: P40938, A0A024RDQ8
UniParc: UPI000041C7E5, UPI0000125168
EMBL: CH471075, CX786577, L07541, AL139081, AL160394, AL161891, BC000149, AF484446
Ensembl: ENSG00000133119
KO: hsa:5983
Nucleutide sequences
EMBL-CDS: EAX08537.1, AAB07268.1, AAH00149.1, AAL82505.1, EAX08538.1
Gene_ORFName: hCG_32194
Ensembl_TRS: ENST00000434425, ENST00000380071
Protein sequencees
Ensembl_PRO: ENSP00000401001, ENSP00000369411
RefSeq: XP_016876171.1, XP_011533474.1, XP_011533476.1, XP_016876172.1, NP_853536.2, XP_011533477.1, NP_002906.1, XP_016876169.1, XP_016876170.1, XP_011533475.1
Others
UniRef100: UniRef100_P40938
UniRef90: UniRef90_P40938
UniRef50: UniRef50_P40938
UniGene: Hs.115474
CCDS: CCDS9352.1, CCDS45025.1

全选

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