| Type | Description |
|---|---|
| Definition | REV3 like, DNA directed polymerase zeta catalytic subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:36:00 | Translesion synthesis of 6-nitrochrysene-derived 2'-deoxyadenosine adduct in human cells. | 32721818 |
| 2020-11-21 13:35:00 | Blood mRNA expression of REV3L and TYMS as potential predictive biomarkers from platinum-based chemotherapy plus pemetrexed in non-small cell lung cancer patients. | 31832811 |
| 2020-11-21 13:27:00 | Mutant POLQ and POLZ/REV3L DNA polymerases may contribute to the favorable survival of patients with tumors with POLE mutations outside the exonuclease domain. | 32838755 |
| 2020-07-11 12:30:00 | A post-translational cleavage event plays a vital role in controlling REV3L stability by preventing ubiquitination and proteasome-mediated degradation of REV3L | 32064513 |
| 2020-01-18 12:15:00 | miR-145 was downregulated in esophageal squamous cell carcinoma (ESCC) tumor tissues and cells, while REV3L was upregulated in ESCC tumor tissues. Overexpression of miR-145 decreased REV3L mRNA and protein level in ESCC cell line KYSE150, while decreased miR-145 increased REV3L mRNA and protein level in esophageal epithelium cell line (HEEC). | 31072625 |
| Type | IDs |
|---|---|
| Synonymous | POLZ, REV3 |
| Gene |
UniProtKB-ID:
REV3L_HUMAN,
Q9UG47_HUMAN
UniprotKB:
O60673,
Q9UG47
UniParc:
UPI000006FB16,
UPI000013EF7F,
UPI0000140023
EMBL:
AF035537,
AF157476,
AY684169,
AF071798,
AL080317,
AL512325,
AF058701,
AL096744,
AF179429,
AF179428,
AF078695,
AL136310
Ensembl:
ENSG00000009413
KO:
hsa:5980
|
| Nucleutide sequences |
EMBL-CDS:
AAC28460.1,
AAT74627.1,
AAC24009.1,
AAG09402.1,
AAD40184.1,
AAB88486.1,
AAG09403.1,
AAC24357.1,
CAB62529.1
Ensembl_TRS:
ENST00000435970,
ENST00000358835,
ENST00000368802
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000351697,
ENSP00000402003,
ENSP00000357792
RefSeq:
NP_001359007.1,
XP_011534332.1,
NP_001273361.1,
NP_001273360.1,
XP_016866644.1,
XP_016866642.1,
XP_011534333.1,
XP_011534331.1,
XP_016866641.1,
XP_011534338.1,
XP_011534334.1,
XP_011534330.1,
XP_016866643.1,
NP_002903.3
|
| Others |
UniRef100:
UniRef100_O60673,
UniRef100_Q9UG47
UniRef90:
UniRef90_O60673,
UniRef90_A0A087WZU4
UniRef50:
UniRef50_A0A087WZU4,
UniRef50_O60673
UniGene:
Hs.232021
CCDS:
CCDS5091.2,
CCDS69177.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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