| Type | Description |
|---|---|
| Definition | double PHD fingers 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:22:00 | BAF45D knockdown decreases cell viability, inhibits colony formation, induces cell apoptosis and S-phase arrest in human pancreatic cancer cells. | 32024442 |
| 2018-12-22 12:15:00 | de novo variants in DPF2 cause Coffin-Siris syndrome and propose a dominant-negative mechanism of pathogenicity. | 29429572 |
| 2018-05-26 10:09:00 | Authors show that DPF2 interacts with the acetylated tails of both histones 3 and 4 via bipartite binding pockets on the DPF2 surface. Blocking these interactions through targeted mutagenesis of DPF2 abolishes its recruitment to target chromatin regions as well as its ability to prevent myeloid differentiation in vivo. | 28533407 |
| 2017-07-29 12:03:00 | Upon influenza virus infection, DPF2 dysregulated IFN-beta induction and expression of cytokines/chemokines and antiviral proteins. This study provides evidence that influenza virus utilizes DPF2 to escape host innate immunity. | 28404846 |
| 2017-05-13 20:12:00 | The demonstrate that the histone acetylation-binding double PHD finger (DPF) domains of human MOZ (also known as KAT6A) and DPF2 (also known as BAF45d) accommodate a wide range of histone lysine acylation with the strongest preference for propionylation (Kcr). | 27775714 |
| Type | IDs |
|---|---|
| Synonymous | CSS7, REQ, UBID4, ubi-d4 |
| Gene |
UniProtKB-ID:
REQU_HUMAN,
A0A024R582_HUMAN,
J3KMZ8_HUMAN
UniprotKB:
Q92785,
A0A024R582,
J3KMZ8
UniParc:
UPI000000D90F,
UPI00017A7B37,
UPI000014F5EF
EMBL:
AF001433,
CH471076,
AK291944,
U43920,
BC014889,
BT006718,
U94585,
AP000944,
AK300061,
AY220877
Ensembl:
ENSG00000133884
KO:
hsa:5977
|
| Nucleutide sequences |
EMBL-CDS:
AAO26041.1,
EAW74375.1,
AAP35364.1,
AAB81203.1,
BAG61870.1,
AAB58307.1,
BAF84633.1,
AAH14889.1,
AAC50687.1,
EAW74376.1
Gene_ORFName:
hCG_23274
Ensembl_TRS:
ENST00000415073,
ENST00000528416,
ENST00000252268
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000399714,
ENSP00000436901,
ENSP00000252268
RefSeq:
XP_016873590.1,
NP_006259.1,
NP_001317237.1,
XP_016873591.1,
XP_024304405.1,
XP_024304406.1
|
| Others |
UniRef100:
UniRef100_J3KMZ8,
UniRef100_Q92785
UniRef90:
UniRef90_J3KMZ8,
UniRef90_Q92785
UniRef50:
UniRef50_Q92785
UniGene:
Hs.13495
CCDS:
CCDS8100.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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