Type | Description |
---|---|
Definition | RecQ like helicase |
Date | Results | Publications |
---|---|---|
2021-04-17 13:15:00 | Genome-Wide Analysis Unveils DNA Helicase RECQ1 as a Regulator of Estrogen Response Pathway in Breast | 33468559 |
2021-03-20 13:31:00 | RECQ1 Helicase in Genomic Stability and Cancer. | 32517021 |
2020-08-15 19:06:00 | RECQL5 plays an essential role in maintaining genome stability and viability of triple-negative breast cancer cells. | 31231988 |
2020-06-27 10:40:00 | Dual deficiency of MUS81 structure-specific endonuclease subunit (MUS81) and RECQ1 increased gemcitabine-induced, replication-associated DNA double-stranded breaks. | 31444271 |
2020-01-18 11:48:00 | EXD2 deficiency leads to fork collapse, hypersensitivity to replication inhibitors, and genomic instability. Impeding fork regression by inactivation of SMARCAL1 or removal of RECQ1's inhibition in EXD2(-/-) cells restores efficient fork restart and genome stability. Moreover, purified EXD2 efficiently processes substrates mimicking regressed forks. | 31255466 |
Type | IDs |
---|---|
Synonymous | RECQL1, RecQ1 |
Gene |
UniProtKB-ID:
RECQ1_HUMAN,
A0A024RAV2_HUMAN
UniprotKB:
P46063,
A0A024RAV2
UniParc:
UPI0000167E2F
EMBL:
BT007119,
AK291627,
BC001052,
AC006559,
D37984,
L36140,
CH471094
Ensembl:
ENSG00000004700
KO:
hsa:5965
|
Nucleutide sequences |
EMBL-CDS:
AAP35783.1,
EAW96434.1,
BAA07200.1,
AAH01052.1,
AAA60261.1,
BAF84316.1,
EAW96438.1,
EAW96436.1,
EAW96437.1,
EAW96435.1
Gene_ORFName:
hCG_2009728
Ensembl_TRS:
ENST00000421138,
ENST00000444129
|
Protein sequencees |
Ensembl_PRO:
ENSP00000416739,
ENSP00000395449
RefSeq:
NP_002898.2,
XP_005253521.1,
XP_005253519.1,
XP_005253520.1,
NP_116559.1,
XP_005253518.1
|
Others |
UniRef100:
UniRef100_P46063
UniRef90:
UniRef90_P46063
UniRef50:
UniRef50_P46063
UniGene:
Hs.235069
CCDS:
CCDS31756.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员